van der Valk P G, Maibach H I
Department of Dermatology, School of Medicine, University of California, San Francisco 94143.
Clin Exp Dermatol. 1990 May;15(3):180-2. doi: 10.1111/j.1365-2230.1990.tb02068.x.
The functional role of different layers of the horny layer in preventing evaporative water loss was studied by an adhesive cellophane-tape stripping technique. The increase in transepidermal water loss, as described by a mathematical equation based on curve-fitting analysis, was shown to be proportional to the decrease in thickness of the horny layer. In the second half of the curve the experimental data showed slightly higher transepidermal-water-loss values than would be expected on the basis of proportionality with thickness of the stratum corneum. The data suggest that the outer layers of the horny layer are also important in forming a barrier to evaporative water loss.
采用粘性玻璃纸胶带剥离技术研究了角质层不同层次在防止水分蒸发流失方面的功能作用。基于曲线拟合分析的数学方程所描述的经表皮水分流失增加量，与角质层厚度的减少成正比。在曲线后半段，实验数据显示经表皮水分流失值略高于基于与角质层厚度成比例关系所预期的值。数据表明角质层外层在形成防止水分蒸发流失的屏障方面也很重要。
