Al-Ghamdi Ahmad S, Aljohani Naji
Specialized Diabetes and Endocrine Center, King Fahad Medical City, Riyadh, Saudi Arabia.
Clin Med Insights Case Rep. 2013 Mar 27;6:47-50. doi: 10.4137/CCRep.S10534. Print 2013.
The objective of this report is to present a case of Graves' thyrotoxicosis-induced cardiomyopathy. This is a case of a 26 year old woman that presented with severe symptomatic congestive heart failure and was subsequently diagnosed with dilated cardiomyopathy secondary to Graves' disease. Despite an initial left ventricular systolic ejection fraction of 20% on echocardiography, treatment with anti-thyroid agents led to rapid improvement of her clinical status and normalization of her ejection fraction. The proposed mechanisms underlying the development of systolic dysfunction in thyrotoxicosis are discussed and the literature on similar cases previously reported is highlighted. Cardiomyopathy should be considered even in young patients with Graves' thyrotoxicosis.
本报告的目的是介绍一例格雷夫斯甲状腺毒症诱发的心肌病病例。这是一名26岁女性患者，表现为严重的症状性充血性心力衰竭，随后被诊断为继发于格雷夫斯病的扩张型心肌病。尽管超声心动图最初显示左心室收缩射血分数为20%，但使用抗甲状腺药物治疗后，她的临床状况迅速改善，射血分数恢复正常。文中讨论了甲状腺毒症时收缩功能障碍发生的潜在机制，并着重介绍了先前报道的类似病例的文献。即使是患有格雷夫斯甲状腺毒症的年轻患者，也应考虑到心肌病的可能。
