Ebisawa K, Ikeda U, Murata M, Sekiguchi H, Nagai R, Yazaki Y, Shimada K
Department of Cardiology, Jichi Medical School, Tochigi, Japan.
Cardiology. 1994;84(4-5):274-7. doi: 10.1159/000176411.
We report 4 adult patients with thyrotoxicosis accompanied by irreversible low-output heart failure. Each patient showed elevated plasma levels of thyroid hormone and prolonged low-output heart failure even after thyroid function returned to normal. Specimens of the right ventricular myocardium stained with anti-beta myosin heavy-chain MAb showed a normal staining pattern with a predominance of the beta-form. Our observations suggest that thyrotoxicosis may be one possible cause of irreversible cardiomyopathy.
我们报告了4例伴有不可逆性低输出量心力衰竭的成年甲状腺毒症患者。每位患者甲状腺激素血浆水平均升高，即使甲状腺功能恢复正常后仍存在持续性低输出量心力衰竭。用抗β肌球蛋白重链单克隆抗体染色的右心室心肌标本显示出正常的染色模式，以β型为主。我们的观察结果表明，甲状腺毒症可能是不可逆性心肌病的一个可能原因。
