Antila K J, Välimäki I A, Mäkelä M, Tuominen J, Wilson A J, Southall D P
Cardiorespiratory Research Unit, University of Turku, Finland.
Early Hum Dev. 1990 May;22(2):57-72. doi: 10.1016/0378-3782(90)90080-3.
To study the role of the autonomic cardiovascular control in SIDS the heart rate variability (HRV) was analysed from 24 tape recordings made from a prospective population-based study on 16 term and one preterm infant suffering SIDS and compared to similar data on 23 control infants matched on birthweight, gestation and postnatal age. The number of regular breathing segments was lower in the SIDS cases than in controls (P = 0.02). No significant differences were found between the SIDS cases and their controls for average heart rate, median breathing rate, indices of overall and beat-to-beat HRV. Neither were significant intergroup differences found when the subjects were divided into neonatal and postneonatal subgroups. Analysis of HRV by power-spectral techniques did not show any significant differences between SIDS cases and controls for the general distribution of power or for the respiratory HRV. Analysis of HRV did not differentiate infants destined to die of SIDS from surviving controls in the same population.
为研究自主心血管控制在婴儿猝死综合征（SIDS）中的作用，我们对一项基于人群的前瞻性研究中的24份磁带记录进行了心率变异性（HRV）分析。该研究涉及16名足月儿和1名早产儿，他们均患有SIDS，并与23名在出生体重、孕周和出生后年龄相匹配的对照婴儿的类似数据进行了比较。SIDS病例中规律呼吸段的数量低于对照组（P = 0.02）。在平均心率、呼吸中位数、总体和逐搏HRV指数方面，SIDS病例与其对照组之间未发现显著差异。当将受试者分为新生儿和新生儿后期亚组时，组间也未发现显著差异。通过功率谱技术对HRV进行分析，在功率的总体分布或呼吸HRV方面，SIDS病例与对照组之间未显示出任何显著差异。HRV分析未能区分同一人群中注定死于SIDS的婴儿与存活的对照组。
