Cooper E S, Bundy D A, MacDonald T T, Golden M H
Tropical Metabolism Research Unit, University of the West Indies, Kingston, Jamaica.
Eur J Clin Nutr. 1990 Apr;44(4):285-91.
The Trichuris Dysentery Syndrome (Ramsey, 1962) is an insidious, chronic condition which has clinical features similar to Crohn's ileocolitis and ulcerative colitis, diseases similarly associated with growth retardation. The attained heights and weights of 19 children at the time of diagnosis of intens, -2.4 Standard Deviation (Z) scores from the Tanner-Whitehouse median with weight, adjusted for height-age, -1.3 Z. We present data on the growth velocities of 11 of the children in the half-year following worm expulsion by mebendazole. These children returned to their home environments without food supplementation or close follow-up, but showed an average height velocity of +5.5 Z and weight velocity (for height-age) of +2.4 Z. Of 8 children with unequivocal height spurts only 3 had any weight spurt. We suggest that the pattern of catch-up growth points to the existence of some specific link between allergy or inflammation in the lower intestinal tract and suppression of linear growth, rather than to stunting due to general deprivation and undernutrition.
鞭虫痢疾综合征（拉姆齐，1962年）是一种隐匿的慢性疾病，其临床特征与克罗恩病性回结肠炎和溃疡性结肠炎相似，这些疾病同样与生长发育迟缓有关。19名儿童在诊断时的身高和体重，与坦纳 - 怀特豪斯中位数相比，体重的标准差（Z）评分为 -2.4，根据身高年龄调整后的体重Z评分为 -1.3。我们展示了11名儿童在服用甲苯达唑驱虫后的半年内的生长速度数据。这些儿童回到他们的家庭环境中，没有食物补充或密切随访，但平均身高速度为 +5.5Z，体重速度（根据身高年龄）为 +2.4Z。在8名有明确身高突增的儿童中，只有3名有体重突增。我们认为，追赶生长模式表明下肠道的过敏或炎症与线性生长抑制之间存在某种特定联系，而不是由于普遍贫困和营养不良导致的发育迟缓。
