Shier Anna C, Reichenbacher Thomas, Ghuman Harinder S, Ghuman Jaswinder K
J Cent Nerv Syst Dis. 2012 Dec 20;5:1-17. doi: 10.4137/JCNSD.S6691. Print 2013.
Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder of childhood that can result in significant functional impairment, and if not adequately treated can lead to impaired quality of life. Pharmacotherapy is considered the first-line treatment for ADHD in children and adolescents. We review both recent literature and seminal studies regarding the pharmacological treatment of ADHD in children and adolescents. There is ample evidence for the efficacy and safety of both stimulants and non-stimulants in the treatment of ADHD. We review important aspects of evaluation and assessment and discuss first-line pharmacological treatments and as well as when to consider using alternative pharmacological agents. Treatment approaches to manage frequently seen comorbid disorders with ADHD are also covered.
注意力缺陷多动障碍(ADHD)是一种常见的儿童神经行为障碍,可导致严重的功能损害,若未得到充分治疗会导致生活质量受损。药物治疗被认为是儿童和青少年ADHD的一线治疗方法。我们回顾了关于儿童和青少年ADHD药物治疗的近期文献和经典研究。有充分证据表明兴奋剂和非兴奋剂在治疗ADHD方面的有效性和安全性。我们回顾了评估和评定的重要方面,并讨论一线药物治疗以及何时考虑使用替代药物。还涵盖了处理ADHD常见共病障碍的治疗方法。