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阐明儿童新兴呼吸道病毒感染的临床作用。

Elucidation and clinical role of emerging viral respiratory tract infections in children.

机构信息

Department of Pediatrics, Radboud University Medical Centre, Nijmegen, The Netherlands.

出版信息

Adv Exp Med Biol. 2013;764:191-204. doi: 10.1007/978-1-4614-4726-9_16.

Abstract

Acute respiratory viral infections (ARVI's) are the most common infectious disease in humans. With the appearance of molecular techniques the recovery of viruses has dramatically increased. Nowadays virologists can quickly discriminate virological families and related viruses from emerging viruses and consequently identify novel viruses. Many new respiratory viruses have been identified in children in the past 15 years. In this review we shortly discuss novel respiratory viruses and their pathogenic role in pediatric respiratory disease. Advantages and drawbacks of the technique and our current knowledge will be discussed. We will conclude this review with a general discussion on the future role of molecular diagnostic virology in the clinic.

摘要

急性呼吸道病毒感染(ARVI)是人类最常见的传染病。随着分子技术的出现,病毒的恢复量大大增加。如今,病毒学家能够快速区分病毒科及其相关病毒与新兴病毒,并因此识别出新的病毒。在过去的 15 年中,儿科领域已经发现了许多新的呼吸道病毒。在这篇综述中,我们简要讨论了新型呼吸道病毒及其在儿科呼吸道疾病中的致病作用。我们将讨论该技术的优缺点以及我们目前的认识。最后,我们将对分子诊断病毒学在临床上的未来作用进行一般性讨论。

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本文引用的文献

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Hendra virus: what do we know?亨德拉病毒:我们了解多少?
N S W Public Health Bull. 2011 Jul;22(5-6):118-22. doi: 10.1071/NB10077.
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Viral pneumonia.病毒性肺炎。
Lancet. 2011 Apr 9;377(9773):1264-75. doi: 10.1016/S0140-6736(10)61459-6. Epub 2011 Mar 22.

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