Waniczek Dariusz, Rubicz Nina, Rudzki Marek, Buda Krzysztof, Arendt Jerzy
Katedra i Oddział Kliniczny Chirurgii Ogólnej i Gastroenterologicznej, Wydział Lekarski z Oddziałem Lekarsko-Dentystycznym w Zabrzu, Slaski Uniwersytet Medyczny w Katowicach.
Wiad Lek. 2012;65(4):220-4.
Solitary rectal ulcer syndrome (SRUS) is a chronic, benign, polymorphic disease of the rectum, the final diagnosis of which is based on histopathologic criteria. Microscopic examination shows glandular changes, oedema and obliteration of the normal architecture in the region of the lamina propria, with muslce fibre penetrating into lamina. Although SRUS pathogenesis is bound up with defecation disorder, it still remains unclear. Disease symptoms are nonspecific--in most cases defecation disorders appear (incomplete defecation, blood and mucus in stool). In some patients emotional disorders can be observed. SRUS treatment is a complex and long-lasting process. Usually it is ineffective or gives only passing effects. SRUS can often be accompanied by rectal prolapse, sometimes a hidden one. In these cases there are more therapeutic possibilities and the prognosis is slightly better. There is no method of choice for SRUS treatment and the prognosis is hard to predict. The treatment should be selected individually, depending on the symptoms intensity and the occurrence of rectal prolapse.
孤立性直肠溃疡综合征（SRUS）是一种直肠的慢性、良性、多形性疾病，其最终诊断基于组织病理学标准。显微镜检查显示固有层区域的腺体变化、水肿以及正常结构的消失，伴有肌纤维穿透固有层。虽然SRUS的发病机制与排便障碍有关，但仍不清楚。疾病症状不具有特异性——在大多数情况下会出现排便障碍（排便不尽、粪便中带血和黏液）。在一些患者中可观察到情绪障碍。SRUS的治疗是一个复杂且持久的过程。通常效果不佳或只是暂时有效。SRUS常伴有直肠脱垂，有时是隐匿性的。在这些情况下有更多的治疗可能性且预后稍好。SRUS治疗没有选择的方法且预后难以预测。应根据症状的严重程度和直肠脱垂的发生情况进行个体化治疗。
