Department of Microbiology, Faculty of Biology, Moscow State University, Moscow, Russia.
PLoS One. 2013 Apr 26;8(4):e62808. doi: 10.1371/journal.pone.0062808. Print 2013.
Here we show that carbon dioxide (CO2) stimulates budding and shortens the lag-period of Saccharomyces cerevisiae cultures, grown on specific weak media. CO2 can be both exogenous and secreted by another growing yeast culture. We also show that this effect can be observed only in the lag-period, and demonstrate minimal doses and duration of culture exposition to CO2. Opposite to the effects of CO2 sensitivity, previously shown for pathogens, where increased concentration of CO2 suppressed mitosis and stimulated cell differentiation and invasion, here it stimulates budding and culture growth.
在这里，我们展示了二氧化碳（CO2）可以刺激酿酒酵母培养物的出芽，并缩短其延迟期，这些培养物生长在特定的弱培养基上。CO2 既可以是外源性的，也可以由另一种生长的酵母培养物分泌。我们还表明，这种效应只能在延迟期观察到，并证明了 CO2 对培养物暴露的最小剂量和持续时间。与先前显示的病原体对 CO2 敏感性的影响相反，在这里，高浓度的 CO2 会抑制有丝分裂，刺激细胞分化和侵袭，而在这里，它会刺激出芽和培养物生长。
