霍乱毒素对家兔小肠黏膜中ATP酶活性的影响。
Effect of cholera toxin on ATPase activities in rabbit small intestinal mucosa.
作者信息
Shubin V S, Yurkiev V A
机构信息
Laboratory for Molecular Mechanisms of Infections, Central Research Institute of Epidemiology, Moscow, Russia.
出版信息
Bull Exp Biol Med. 2013 Apr;154(6):744-6. doi: 10.1007/s10517-013-2045-0.
PMID:23658913
Abstract
Cholera toxin induced the appearance of ATPase activity in rabbit small intestinal mucosa. This enzyme significantly differed from other ATPases, including Na(+),K(+)-ATPase and HCO3(-)-ATPase in the small intestinal epithelium of rabbits, by some properties, in particular, by relation to divalent and monovalent cations and anions, pH optimum, substrate specificity, and inhibitory analysis.
摘要
霍乱毒素可诱导兔小肠黏膜中ATP酶活性的出现。这种酶在某些特性上，特别是在与二价和一价阳离子及阴离子的关系、最适pH值、底物特异性和抑制分析等方面，与其他ATP酶有显著差异，这些其他ATP酶包括兔小肠上皮中的钠钾ATP酶和碳酸氢根ATP酶。
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