Lopatina I A, Lopatkina T N, Tanashchuk E L, Arion E A
Klin Med (Mosk). 2013;91(1):66-70.
Two clinical observations of the variant form of hepatic lesion: autoimmune hepatitis--primary biliary cirrhosis with systemic manifestations are presented in patients with long-standing Sjogren's syndrome, one at the stage of lever cirrhosis, the other at stage F2 of fibrosis. Difficulties encountered in diagnostics and the necessity of changing the entire spectrum of autoimmune markers characteristic of Sjogren's syndrome, autoimmune hepatitis and primary biliary cirrhosis are discussed. The possibility of different forms of hepatic lesions in autoimmune hepatitis--primary biliary cirrhosis is emphasized.
自身免疫性肝炎——原发性胆汁性肝硬化合并全身表现,见于长期患有干燥综合征的患者,一例处于肝硬化阶段,另一例处于纤维化F2期。文中讨论了诊断中遇到的困难以及改变干燥综合征、自身免疫性肝炎和原发性胆汁性肝硬化所特有的自身免疫标志物全谱的必要性。强调了自身免疫性肝炎——原发性胆汁性肝硬化中存在不同形式肝病变的可能性。