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Int J Food Microbiol. 2012 Jun 1;156(3):231-8. doi: 10.1016/j.ijfoodmicro.2012.03.029. Epub 2012 Apr 5.
2
The etiology of severe acute gastroenteritis among adults visiting emergency departments in the United States.美国急诊科就诊成人严重急性胃肠炎的病因。
J Infect Dis. 2012 May 1;205(9):1374-81. doi: 10.1093/infdis/jis206. Epub 2012 Mar 27.
3
Prevalence of shiga toxin-producing Escherichia coli as detected by enzyme-linked immunoassays and real-time PCR during the summer months in northern Alberta, Canada.加拿大阿尔伯塔省北部夏季通过酶联免疫吸附测定法和实时 PCR 检测产志贺毒素大肠杆菌的流行情况。
J Clin Microbiol. 2011 Dec;49(12):4307-10. doi: 10.1128/JCM.05211-11. Epub 2011 Sep 21.
4
Rotavirus in adults requiring hospitalization.成人住院患者中的轮状病毒。
J Infect. 2012 Jan;64(1):89-95. doi: 10.1016/j.jinf.2011.09.003. Epub 2011 Sep 16.
5
Risk-based estimate of effect of foodborne diseases on public health, Greece.基于风险的食源性疾病对公众健康影响的估计,希腊。
Emerg Infect Dis. 2011 Sep;17(9):1581-90. doi: 10.3201/eid1709.101766.
6
Longitudinal study of infectious intestinal disease in the UK (IID2 study): incidence in the community and presenting to general practice.英国传染性肠道疾病的纵向研究(IID2 研究):社区发病率和向全科医生就诊情况。
Gut. 2012 Jan;61(1):69-77. doi: 10.1136/gut.2011.238386. Epub 2011 Jun 27.
7
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Emerg Infect Dis. 2011 Jan;17(1):16-22. doi: 10.3201/eid1701.091101p2.
8
Foodborne illness acquired in the United States--major pathogens.食源性疾病在美国的感染情况——主要病原体。
Emerg Infect Dis. 2011 Jan;17(1):7-15. doi: 10.3201/eid1701.p11101.
9
The impact of international travel on the epidemiology of enteric infections, British Columbia, 2008.2008 年不列颠哥伦比亚省肠道感染病流行病学:国际旅行的影响
Can J Public Health. 2010 Jul-Aug;101(4):332-6. doi: 10.1007/BF03405297.
10
Foodborne proportion of gastrointestinal illness: estimates from a Canadian expert elicitation survey.食源性胃肠道疾病比例:来自加拿大专家 elicitation 调查的估计。
Foodborne Pathog Dis. 2010 Dec;7(12):1463-72. doi: 10.1089/fpd.2010.0582. Epub 2010 Aug 12.

2006 年加拿大 30 种特定病原体和未特定病原体食源性疾病负担估计。

Estimates of the burden of foodborne illness in Canada for 30 specified pathogens and unspecified agents, circa 2006.

机构信息

Centre for Food-borne , Environmental, and Zoonotic Infectious Diseases, Public Health Agency of Canada, Guelph, Ontario, Canada.

出版信息

Foodborne Pathog Dis. 2013 Jul;10(7):639-48. doi: 10.1089/fpd.2012.1389. Epub 2013 May 9.

DOI:10.1089/fpd.2012.1389
PMID:23659355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3696931/
Abstract

Estimates of foodborne illness are important for setting food safety priorities and making public health policies. The objective of this analysis is to estimate domestically acquired, foodborne illness in Canada, while identifying data gaps and areas for further research. Estimates of illness due to 30 pathogens and unspecified agents were based on data from the 2000-2010 time period from Canadian surveillance systems, relevant international literature, and the Canadian census population for 2006. The modeling approach required accounting for under-reporting and underdiagnosis and to estimate the proportion of illness domestically acquired and through foodborne transmission. To account for uncertainty, Monte Carlo simulations were performed to generate a mean estimate and 90% credible interval. It is estimated that each year there are 1.6 million (1.2-2.0 million) and 2.4 million (1.8-3.0 million) episodes of domestically acquired foodborne illness related to 30 known pathogens and unspecified agents, respectively, for a total estimate of 4.0 million (3.1-5.0 million) episodes of domestically acquired foodborne illness in Canada. Norovirus, Clostridium perfringens, Campylobacter spp., and nontyphoidal Salmonella spp. are the leading pathogens and account for approximately 90% of the pathogen-specific total. Approximately one in eight Canadians experience an episode of domestically acquired foodborne illness each year in Canada. These estimates cannot be compared with prior crude estimates in Canada to assess illness trends as different methodologies were used.

摘要

食源性疾病的估计对于确定食品安全重点和制定公共卫生政策非常重要。本分析的目的是估计加拿大国内的食源性疾病,并确定数据差距和进一步研究的领域。对 30 种病原体和未指定病原体引起的疾病的估计是基于加拿大监测系统、相关国际文献以及 2006 年加拿大人口普查的 2000-2010 年期间的数据。该模型方法需要考虑漏报和漏诊,并估计国内获得的疾病和通过食源性传播的疾病的比例。为了考虑不确定性,进行了蒙特卡罗模拟以生成平均值估计值和 90%置信区间。估计每年有 160 万(120-200 万)和 240 万(180-300 万)例与 30 种已知病原体和未指定病原体相关的国内获得性食源性疾病,加拿大国内获得性食源性疾病的总估计数为 400 万(310-500 万)例。诺如病毒、产气荚膜梭菌、弯曲菌和非伤寒沙门氏菌是主要病原体,约占病原体总数的 90%。每年约有八分之一的加拿大人在加拿大经历一次国内获得性食源性疾病。由于使用了不同的方法学,这些估计值不能与加拿大以前的粗略估计值进行比较,以评估疾病趋势。