Food Standards Agency, London, UK
Big Data Institute, Oxford, UK.
BMJ Open Gastroenterol. 2020 Jun;7(1). doi: 10.1136/bmjgast-2020-000377.
To estimate the number of deaths from foodborne disease in the UK from 11 key pathogens.
Four different models were developed using data from a range of sources. These included enhanced surveillance, outbreaks, death certificates and hospital episode statistics data. For each model, median estimates were produced with 95% credible intervals (CrI). The results from the different models were compared.
The estimates for foodborne deaths for each pathogen from the different models were consistent, with CrIs largely overlapping. Based on the preferred model for each pathogen, foodborne norovirus is estimated to cause 56 deaths per year (95% CrI 32 to 92), foodborne 33 deaths (95% CrI 7 to 159), foodborne 26 deaths (95% CrI 24 to 28), foodborne 25 deaths (95% CrI 1 to 163) and foodborne 21 deaths (95% CrI 8 to 47). The considerable overlap in the CrIs means it is not possible to make any firm conclusions on ranking. Most of these deaths occur in those aged over 75 years. Foodborne deaths from , , adenovirus, astrovirus and rotavirus are all rare.
We estimate that there are 180 deaths per year in the UK (95% CrI 113 to 359) caused by foodborne disease based on these 11 pathogens. While this is a small fraction of the estimated 2.4 million cases of foodborne illness per year it still illustrates the potential severity of these illnesses demonstrating the importance in continuing efforts to reduce these infections.
估计英国 11 种主要病原体引起的食源性疾病死亡人数。
使用来自多种来源的数据开发了四种不同的模型。这些模型包括强化监测、暴发、死亡证明和住院事件统计数据。对于每个模型,都生成了中位数估计值和 95%可信区间(CrI)。比较了不同模型的结果。
不同模型对每种病原体的食源性死亡估计数是一致的,CrI 大部分重叠。基于每个病原体的首选模型,食源性诺如病毒估计每年导致 56 人死亡(95% CrI 32 至 92),食源性 33 人死亡(95% CrI 7 至 159),食源性 26 人死亡(95% CrI 24 至 28),食源性 25 人死亡(95% CrI 1 至 163)和食源性 21 人死亡(95% CrI 8 至 47)。CrI 的大量重叠意味着无法对排名做出任何明确的结论。这些死亡大多发生在 75 岁以上的人群中。食源性感染、、腺病毒、星状病毒和轮状病毒引起的死亡都很罕见。
根据这 11 种病原体,我们估计英国每年有 180 人(95% CrI 113 至 359)死于食源性疾病。虽然这只是每年估计的 240 万例食源性疾病病例的一小部分,但它仍然说明了这些疾病的潜在严重性,表明继续努力减少这些感染的重要性。