Trimbos-instituut and ICASA Foundation, Utrecht, The Netherlands; Amsterdam Institute for Addiction Research, Amsterdam, The Netherlands.
Drug Alcohol Depend. 2013 Oct 1;132(3):587-96. doi: 10.1016/j.drugalcdep.2013.04.010. Epub 2013 May 6.
To detect attention deficit hyperactivity disorder (ADHD) in treatment seeking substance use disorders (SUD) patients, a valid screening instrument is needed.
To test the performance of the Adult ADHD Self-Report Scale V 1.1(ASRS) for adult ADHD in an international sample of treatment seeking SUD patients for DSM-IV-TR; for the proposed DSM-5 criteria; in different subpopulations, at intake and 1-2 weeks after intake; using different scoring algorithms; and different externalizing disorders as external criterion (including adult ADHD, bipolar disorder, antisocial and borderline personality disorder).
In 1138 treatment seeking SUD subjects, ASRS performance was determined using diagnoses based on Conner's Adult ADHD Diagnostic Interview for DSM-IV (CAADID) as gold standard.
The prevalence of adult ADHD was 13.0% (95% CI: 11.0-15.0%). The overall positive predictive value (PPV) of the ASRS was 0.26 (95% CI: 0.22-0.30), the negative predictive value (NPV) was 0.97 (95% CI: 0.96-0.98). The sensitivity (0.84, 95% CI: 0.76-0.88) and specificity (0.66, 95% CI: 0.63-0.69) measured at admission were similar to the sensitivity (0.88, 95% CI: 0.83-0.93) and specificity (0.67, 95% CI: 0.64-0.70) measured 2 weeks after admission. Sensitivity was similar, but specificity was significantly better in patients with alcohol compared to (illicit) drugs as the primary substance of abuse (0.76 vs. 0.56). ASRS was not a good screener for externalizing disorders other than ADHD.
The ASRS is a sensitive screener for identifying possible ADHD cases with very few missed cases among those screening negative in this population.
为了在寻求治疗的物质使用障碍(SUD)患者中检测注意缺陷多动障碍(ADHD),需要一种有效的筛查工具。
在寻求治疗的 SUD 患者的国际样本中,测试成人 ADHD 自我报告量表第五版 1.1(ASRS)用于 DSM-IV-TR 的成人 ADHD 的表现;用于 DSM-5 提出的标准;在不同的亚人群中,在入院时和入院后 1-2 周;使用不同的评分算法;以及不同的外化障碍作为外部标准(包括成人 ADHD、双相情感障碍、反社会和边缘型人格障碍)。
在 1138 名寻求治疗的 SUD 受试者中,使用基于康纳成人 ADHD 诊断访谈 DSM-IV(CAADID)的诊断作为金标准,确定 ASRS 的表现。
ADHD 的患病率为 13.0%(95%CI:11.0-15.0%)。ASRS 的总体阳性预测值(PPV)为 0.26(95%CI:0.22-0.30),阴性预测值(NPV)为 0.97(95%CI:0.96-0.98)。入院时的灵敏度(0.84,95%CI:0.76-0.88)和特异性(0.66,95%CI:0.63-0.69)与入院后 2 周时的灵敏度(0.88,95%CI:0.83-0.93)和特异性(0.67,95%CI:0.64-0.70)相似。在以酒精为主要滥用药物的患者中,灵敏度相似,但特异性明显优于(非法)药物(0.76 对 0.56)。ASRS 不是筛选 ADHD 以外的外化障碍的良好工具。
ASRS 是一种敏感的筛查工具,可在该人群中筛查阴性的情况下,很少漏诊可能的 ADHD 病例。