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筛查边缘型人格障碍中的注意缺陷/多动障碍。

Screening for attention-deficit/hyperactivity disorder in borderline personality disorder.

机构信息

Department of Psychiatry, University Hospital of Strasbourg, Strasbourg, France; Department of Mental Health and Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.

Department of Mental Health and Psychiatry, University Hospitals of Geneva, Geneva, Switzerland.

出版信息

J Affect Disord. 2018 Jan 15;226:85-91. doi: 10.1016/j.jad.2017.09.027. Epub 2017 Sep 23.

DOI:10.1016/j.jad.2017.09.027
PMID:28964997
Abstract

BACKGROUND

A valid screening instrument is needed to detect attention-deficit/hyperactivity disorder (ADHD) in treatment-seeking borderline personality disorder (BPD) patients. We aimed to test the performance of the widely-used Adult ADHD Self-Report Scale v1.1 screener (ASRS-v1.1).

METHODS

317 BPD subjects were systematically assessed for comorbid ADHD and completed the ASRS-v1.1. 79 BPD patients also completed the Wender Utah Rating Scale (WURS-25).

RESULTS

The prevalence of adult ADHD was of 32.4%. The overall positive predictive value of the ASRS-v1.1 was of 38.5%, the negative predictive value 77.0%, the sensitivity 72.8%, and the specificity 43.9%. Combining WURS-25 and ASRS-v1.1 improved sensitivity to 81.8% and specificity to 59.6%.

LIMITATIONS

Cross-sectional study on treatment-seeking patients.

CONCLUSIONS

We found a high prevalence of ADHD using structured interviews. The ASRS-v1.1 was not a sensitive screener for identifying possible ADHD cases in a BPD population, with a high number of false positives. When combined with the WURS-25, it offered improved screening.

摘要

背景

需要一种有效的筛选工具来检测寻求治疗的边缘性人格障碍(BPD)患者的注意力缺陷/多动障碍(ADHD)。我们旨在测试广泛使用的成人 ADHD 自评量表 v1.1 筛查器(ASRS-v1.1)的性能。

方法

317 名 BPD 受试者被系统评估是否存在共患 ADHD,并完成了 ASRS-v1.1。79 名 BPD 患者还完成了 Wender Utah 评定量表(WURS-25)。

结果

成人 ADHD 的患病率为 32.4%。ASRS-v1.1 的总体阳性预测值为 38.5%,阴性预测值为 77.0%,敏感性为 72.8%,特异性为 43.9%。将 WURS-25 和 ASRS-v1.1 结合使用可将敏感性提高到 81.8%,特异性提高到 59.6%。

局限性

这是一项针对寻求治疗的患者的横断面研究。

结论

我们使用结构化访谈发现 ADHD 的患病率较高。ASRS-v1.1 不是 BPD 人群中识别可能 ADHD 病例的敏感筛查工具,假阳性率较高。当与 WURS-25 结合使用时,它提供了更好的筛查。

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