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RiceSRTFDB:一个包含水稻转录因子综合表达、顺式调控元件和突变信息的数据库,以促进基因功能分析。

RiceSRTFDB: a database of rice transcription factors containing comprehensive expression, cis-regulatory element and mutant information to facilitate gene function analysis.

机构信息

Functional and Applied Genomics Laboratory, National Institute of Plant Genome Research, Aruna Asaf Ali Marg, New Delhi 110067, India.

出版信息

Database (Oxford). 2013 May 9;2013:bat027. doi: 10.1093/database/bat027. Print 2013.

DOI:10.1093/database/bat027
PMID:23660286
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3649641/
Abstract

Rice is one of the most important crop plants, representing the staple food for more than half the world's population. However, its productivity is challenged by various stresses, including drought and salinity. Transcription factors (TFs) represent a regulatory component of the genome and are the most important targets for engineering stress tolerance. Here, we constructed a database, RiceSRTFDB, which provides comprehensive expression information for rice TFs during drought and salinity stress conditions and various stages of development. This information will be useful to identify the target TF(s) involved in stress response at a particular stage of development. The curated information for cis-regulatory elements present in their promoters has also been provided, which will be important to study the binding proteins. In addition, we have provided the available mutants and their phenotype information for rice TFs. All these information have been integrated in the database to facilitate the selection of target TFs of interest for functional analysis. This database aims to accelerate functional genomics research of rice TFs and understand the regulatory mechanisms underlying abiotic stress responses. Database URL: http://www.nipgr.res.in/RiceSRTFDB.html

摘要

水稻是最重要的农作物之一,是全球一半以上人口的主食。然而,其生产力受到各种胁迫的挑战,包括干旱和盐度。转录因子(TFs)是基因组的调控组成部分,是工程耐胁迫的最重要目标。在这里,我们构建了一个数据库 RiceSRTFDB,该数据库提供了在干旱和盐度胁迫条件下以及不同发育阶段水稻 TFs 的综合表达信息。该信息将有助于识别在特定发育阶段参与胁迫反应的目标 TF(s)。还提供了其启动子中存在的顺式调控元件的精心编辑信息,这对于研究结合蛋白非常重要。此外,我们还提供了水稻 TFs 的可用突变体及其表型信息。所有这些信息都已整合到数据库中,以方便选择感兴趣的目标 TF 进行功能分析。该数据库旨在加速水稻 TFs 的功能基因组学研究,并深入了解非生物胁迫反应的调控机制。数据库网址:http://www.nipgr.res.in/RiceSRTFDB.html

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/7259dd2ba99e/bat027f3p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/3c4f04c4f8c9/bat027f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/3daf0cca2f0a/bat027f2p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/7259dd2ba99e/bat027f3p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/3c4f04c4f8c9/bat027f1p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/3daf0cca2f0a/bat027f2p.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b69b/3649641/7259dd2ba99e/bat027f3p.jpg

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