Centre for Advanced Research in Environmental Genomics, University of Ottawa, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5.
Food Chem Toxicol. 2013 Aug;58:381-7. doi: 10.1016/j.fct.2013.04.033. Epub 2013 May 9.
Fish, shellfish, wild game, and seaweed are important traditional foods that are essential to the physical and cultural well-being of Indigenous peoples in Canada. The goal of this study was to measure the concentration and bioaccessibility of As, Cd, Hg, Se, Cu and Mn in 45 commonly consumed traditional foods collected by harvested by the First Nations Food, Nutrition, and Environment Study (FNFNES) from 21 First Nations communities in British Columbia, Canada, in 2008-2009. A significant and negative correlation was observed between Hg concentration and Hg bioaccessibility. Metal bioaccessibility tended to be high; median values ranging between 52% (Mn) and 83% (Cu). The notable exceptions were observed for As in wild game organs (7-19%) and rabbit meat (4%) as well as Hg in salmon eggs (10%). Results of Principal Components Analysis confirmed the unique pattern of bioaccessibility of As and Hg in traditional foods, suggesting that, unlike other metals, As and Hg bioaccessibility are not simply controlled by food digestibility under the operating conditions of the in vitro model. These data provide useful information for dietary contaminant risk assessment and intake assessments of essential trace elements.
鱼类、贝类、野生动物和海藻是加拿大原住民传统食物中的重要组成部分，对他们的身心健康至关重要。本研究的目的是测量 2008-2009 年由加拿大不列颠哥伦比亚省 21 个原住民社区的原住民食品、营养和环境研究（FNFNES）收集的 45 种常见传统食物中 As、Cd、Hg、Se、Cu 和 Mn 的浓度和生物可利用性。研究发现 Hg 浓度与 Hg 生物可利用性之间存在显著的负相关关系。金属生物可利用性通常较高，中位数范围在 52%（Mn）至 83%（Cu）之间。只有一些例外，如野生猎物器官（7-19%）和兔肉（4%）中的 As，以及三文鱼卵（10%）中的 Hg。主成分分析的结果证实了传统食物中 As 和 Hg 生物可利用性的独特模式，这表明与其他金属不同，As 和 Hg 生物可利用性并不完全受体外模型操作条件下食物消化率的控制。这些数据为膳食污染物风险评估和必需微量元素摄入量评估提供了有用的信息。
