Department of Dermatology, Allergology and Environmental Medicine, Hospital Munich Schwabing, Koelner Platz 1, Munich 80804, Germany.
Expert Rev Med Devices. 2013 May;10(3):367-77. doi: 10.1586/erd.13.4.
Cold atmospheric plasma science is an innovative upcoming technology for the medical sector. The plasma composition and subsequent effects on cells, tissues and pathogens can vary enormously depending on the plasma source, the plasma settings and the ambient conditions. Cold atmospheric plasmas consist of a highly reactive mix of ions and electrons, reactive molecules, excited species, electric fields and to some extent also UV radiation. In the last year, this partly ionized gas has been demonstrated to have a broad antimicrobial activity, while resistance and resistance development are unlikely. Furthermore, recent research has indicated that plasmas also have a strong influence on various cell lines and cell functions, including anticancer properties. This review summarizes the major plasma designs available and their main benefits, as well as assessing possible risks of this new technology.
低温大气等离子体科学是医疗领域一项创新的新兴技术。等离子体的组成以及对细胞、组织和病原体的后续影响因等离子体源、等离子体设置和环境条件而异。低温大气等离子体由高度反应性的离子和电子、反应性分子、激发态物质、电场以及在某种程度上还有紫外线辐射组成。在过去的一年中，已证明这种部分电离气体具有广谱的抗菌活性，而不太可能产生耐药性和耐药性发展。此外，最近的研究表明，等离子体对各种细胞系和细胞功能也有很强的影响，包括抗癌特性。这篇综述总结了现有的主要等离子体设计及其主要优点，并评估了这项新技术的可能风险。
