Department of Rheumatology, Prince of Wales Hospital, Barker Street, Randwick, Sydney, New South Wales, Australia.
J Clin Rheumatol. 2013 Jun;19(4):203-5. doi: 10.1097/RHU.0b013e3182937abb.
Palmar fasciitis and polyarthritis syndrome is a rare paraneoplastic condition that may portend a diagnosis of malignancy. We describe the case of a 73-year-old man who presented with progressive palmar swelling, erythema, pain, and contractures of both hands, This presentation and associated weight loss eventually led to the diagnosis of metastatic pancreatic adenocarcinoma. This case highlights the often delayed, but important diagnosis of this unusual paraneoplastic phenomenon which can mimic arthropathy, Dupuytren contracture, and scleroderma. Our case is also the first documentation of the extensive inflammatory magnetic resonance imaging changes in palmar fasciitis and polyarthritis syndrome, which affects all tissue planes including the synovium and explains its confusing clinical manifestations.
掌筋膜和多发性关节炎综合征是一种罕见的副肿瘤性疾病，可能预示着恶性肿瘤的诊断。我们描述了一例 73 岁男性，其手部出现进行性掌部肿胀、红斑、疼痛和挛缩。这种表现和相关的体重减轻最终导致转移性胰腺腺癌的诊断。本病例强调了这种不常见的副肿瘤现象的诊断常常被延迟，但却非常重要，因为它可以模仿关节炎、掌腱膜挛缩和硬皮病。我们的病例也是首例掌筋膜和多发性关节炎综合征广泛炎症性磁共振成像改变的记录，它影响所有组织层面，包括滑膜，并解释了其混淆的临床表现。
