Department of Neurology, Chonbuk National University College of Medicine, 634-18 Gumam-dong, Deokjin-gu, Jeonju 561-712, Korea.
J Neurol. 2013 Aug;260(8):2102-9. doi: 10.1007/s00415-013-6953-8. Epub 2013 May 14.
To clarify the changes of cervical (cVEMP) and ocular (oVEMP) vestibular evoked myogenic potentials induced by air-conducted sound (ACS) and bone-conducted vibration (BCV) in patients with vestibular neuritis (VN), patients with VN (n = 30) and normal controls (n = 45) underwent recording of cVEMP and oVEMP in response to ACS (1,000 Hz, 5 ms, tone bursts) and BCV (500 Hz, short tone burst). Patients with VN showed a high proportion of oVEMP abnormalities in response to both ACS (80.0 %) and BCV at the forehead (Fz, 73.3 %) or the mastoid (76.7 %). In contrast, cVEMPs were mostly normal with both ACS and BCV in the patients. The dissociations in the abnormalities of cVEMP and oVEMP induced by ACS and BCV at the mastoids and at the forehead in patients with VN suggest that oVEMP reflects functions of the superior vestibular nerve and most likely the utricular function. The results of our study suggest that oVEMP induced by either ACS or BCV appears to depend on integrity of the superior vestibular nerve, possibly due to the utricular afferents travelling in it. In contrast, cVEMP elicited by either ACS or BCV may reflect function of the saccular afferents running in the inferior vestibular nerve.
为了阐明前庭神经炎（VN）患者经空气传导声（ACS）和骨传导振动（BCV）诱发的颈（cVEMP）和眼（oVEMP）前庭诱发肌源性电位的变化，我们对 30 例 VN 患者和 45 例正常对照者进行了 cVEMP 和 oVEMP 记录，以响应 ACS（1000 Hz，5 ms，短音爆发）和 BCV（500 Hz，短音爆发）。VN 患者对 ACS（80.0%）和 BCV 在额部（Fz，73.3%）或乳突（76.7%）的 oVEMP 异常表现出较高的比例。相比之下，ACS 和 BCV 在患者中均主要表现为 cVEMP 正常。ACS 和 BCV 在乳突和额部诱发的 cVEMP 和 oVEMP 异常的分离表明，oVEMP 反映了上前庭神经的功能，很可能反映了耳石功能。我们的研究结果表明，无论是 ACS 还是 BCV 诱发的 oVEMP 似乎都依赖于上前庭神经的完整性，这可能是由于其中的耳石传入纤维。相比之下，ACS 或 BCV 诱发的 cVEMP 可能反映了在下前庭神经中运行的球囊传入纤维的功能。
