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基于证据的前庭诱发肌源性电位诊断应用:从神经生理学原理到临床应用

Evidence-based diagnostic use of VEMPs : From neurophysiological principles to clinical application.

作者信息

Dlugaiczyk J

机构信息

Deutsches Schwindel- und Gleichgewichtszentrum (DSGZ), Klinikum der Universität München, LMU München, Marchioninistraße 15, 81377, Munich, Germany.

出版信息

HNO. 2020 Aug;68(Suppl 2):69-78. doi: 10.1007/s00106-019-00767-2.

DOI:10.1007/s00106-019-00767-2
PMID:32533211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7403168/
Abstract

BACKGROUND

Vestibular evoked myogenic potentials (VEMPs) are increasingly being used for testing otolith organ function.

OBJECTIVE

This article provides an overview of the anatomical, biomechanical and neurophysiological principles underlying the evidence-based clinical application of ocular and cervical VEMPs (oVEMPs and cVEMPs).

MATERIAL AND METHODS

Systematic literature search in PubMed until April 2019.

RESULTS

Sound and vibration at a frequency of 500 Hz represent selective vestibular stimuli for the otolith organs. The predominant specificity of oVEMPs for contralateral utricular function and of cVEMPs for ipsilateral saccular function is defined by the different central projections of utricular and saccular afferents. VEMPs are particularly useful in the diagnosis of superior canal dehiscence and otolith organ specific vestibular dysfunction and as an alternative diagnostic approach in situations when video oculography is not possible or useful.

CONCLUSION

The use of VEMPs is a simple, safe, reliable and selective test of dynamic function of otolith organs.

摘要

背景

前庭诱发肌源性电位(VEMPs)越来越多地用于检测耳石器官功能。

目的

本文概述了眼性和颈性VEMPs(oVEMPs和cVEMPs)循证临床应用的解剖学、生物力学和神经生理学原理。

材料与方法

截至2019年4月在PubMed上进行系统的文献检索。

结果

500Hz频率的声音和振动是耳石器官的选择性前庭刺激。oVEMPs对侧椭圆囊功能和cVEMPs对同侧球囊功能的主要特异性由椭圆囊和球囊传入神经的不同中枢投射决定。VEMPs在半规管裂和耳石器官特异性前庭功能障碍的诊断中特别有用,并且在无法或不适用视频眼震图的情况下作为一种替代诊断方法。

结论

VEMPs的应用是一种简单、安全、可靠且选择性的耳石器官动态功能检测方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/c68cc5955ec1/106_2019_767_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/8ffcf6a743d3/106_2019_767_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/e186545c1f53/106_2019_767_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/ba699f227140/106_2019_767_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/6e71ff90f069/106_2019_767_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/ed7bc619fb85/106_2019_767_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/c68cc5955ec1/106_2019_767_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/8ffcf6a743d3/106_2019_767_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/e186545c1f53/106_2019_767_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/ba699f227140/106_2019_767_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/6e71ff90f069/106_2019_767_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/ed7bc619fb85/106_2019_767_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f5a/7403168/c68cc5955ec1/106_2019_767_Fig6_HTML.jpg

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