Department of Anatomy, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.
Anat Rec (Hoboken). 2013 Jul;296(7):1083-8. doi: 10.1002/ar.22714. Epub 2013 May 14.
The aim of this study was to provide data on various dimensions of the normal cochlea using three-dimensional reconstruction based on high-resolution micro-CT images. The petrous parts of 39 temporal bones were scanned by micro-computed tomography (CT) with a slice thickness of 35 μm. The micro-CT images were used in reconstructing three-dimensional volumes of the bony labyrinth using computer software. The volumes were used to measure 12 dimensions of the cochlea, and statistical analysis was carried out. The dimensions of cochleae varied widely between different specimens. The mean height and length of the cochlea were 3.8 and 9.7 mm, respectively. The angle between the basal and middle turns was slightly larger in males than in females, while none of the other 11 dimensions differed significantly between males and females. The cochlear accessory canals were observed in about half of the cases (51.3%). Correlation analysis among measured items revealed positive correlations among several of the measured dimensions. The present study could investigate the detailed anatomy of the normal cochlea using high-resolution imaging technologies. The results of the present study could be helpful for the precise diagnosis of congenital cochlear malformations and for producing optimized cochlear implants.
本研究旨在通过基于高分辨率显微 CT 图像的三维重建，提供有关正常耳蜗各个方面的数据。使用厚度为 35μm 的微计算机断层扫描（CT）对 39 个颞骨的岩骨部分进行扫描。使用计算机软件对微 CT 图像进行三维重建，以构建骨迷路的三维容积。使用这些容积来测量耳蜗的 12 个维度，并进行统计分析。不同标本之间的耳蜗尺寸差异很大。耳蜗的平均高度和长度分别为 3.8mm 和 9.7mm。基底圈和中间圈之间的角度在男性中略大于女性，而其余 11 个维度在男性和女性之间没有显著差异。在大约一半的情况下观察到耳蜗辅助通道（51.3%）。对测量项目的相关性分析表明，几个测量维度之间存在正相关。本研究可以使用高分辨率成像技术来研究正常耳蜗的详细解剖结构。本研究的结果有助于对先天性耳蜗畸形的精确诊断，并有助于生产优化的耳蜗植入物。
