Centre National de la Recherche Scientifique (CNRS), GIPSA-Lab, École Doctorale Électronique, Électrotechnique, Automatique, Traitement du Signal (ED EEATS), 38100 Grenoble, France.
Department of Otolaryngology-Head and Neck Surgery, Dijon University Hospital, 21000 Dijon, France.
Sensors (Basel). 2023 Mar 9;23(6):2973. doi: 10.3390/s23062973.
Our work introduces a new robotic solution named CochleRob, which is used for the administration of super-paramagnetic antiparticles as drug carriers into the human cochlea for the treatment of hearing loss caused by damaged cochlea. This novel robot architecture presents two key contributions. First, CochleRob has been designed to meet specifications pertaining to ear anatomy, including workspace, degrees of freedom, compactness, rigidity, and accuracy. The first objective was to develop a safer mathod to administer drugs to the cochlea without the need for catheter or CI insertion. Secondly, we aimed at developing and validating the mathemathical models, including forward, inverse, and dynamic models, to support the robot function. Our work provides a promising solution for drug administration into the inner ear.
我们的工作介绍了一种名为 CochleRob 的新型机器人解决方案，该方案用于将超顺磁反粒子作为药物载体递送到人类耳蜗中，以治疗因耳蜗损伤而导致的听力损失。这种新型机器人结构有两个关键贡献。首先，CochleRob 的设计符合耳朵解剖学的规格，包括工作空间、自由度、紧凑性、刚性和准确性。第一个目标是开发一种更安全的方法将药物递送到耳蜗，而无需导管或 CI 插入。其次，我们旨在开发和验证数学模型，包括正向、逆向和动态模型，以支持机器人功能。我们的工作为将药物递送到内耳提供了一个有前途的解决方案。
Zotero 插件
