Williams Andrew D, Nkombo Yannick, Nkodia Gery, Leonardson Gary, Burd Larry
Department of Pediatrics, North Dakota Fetal Alcohol Syndrome Center, University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota 58203, USA.
Birth Defects Res A Clin Mol Teratol. 2013 Jul;97(7):489-96. doi: 10.1002/bdra.23127. Epub 2013 May 13.
To determine prevalence of prenatal alcohol use in Brazzaville, Congo and to evaluate a prenatal screening tool for use in this population.
A prospective population screening program of 3099 women at 10 prenatal care clinics in Brazzaville, Congo using the 1-Question screen. To validate the 1-Question screen in this population we screened 764 of these women again using the T-ACE as a gold standard for comparison study. The study outcomes were as follows: prevalence of self-reported prenatal alcohol use in Brazzaville using the 1-Question screen, estimation of number of drinking days, drinks per drinking day, most drinks on any one occasion. We also estimated the epidemiologic performance criteria for the 1-Question screen.
The 3099 women screened were classified as follows: no risk 77% (n=2,384); at risk 3.7% (n=115); and as high risk 19.3% (n=600). Of the women reporting drinking during pregnancy, 87.4% reported drinking 4 or more drinks on any occasion. The agreement for detection of alcohol use during pregnancy by the 1-Question Screen and a positive T-ACE score was 94.7%.
23.3% of women attending prenatal care in Brazzaville reported alcohol use during pregnancy and 83% of them continued to drink after recognition of pregnancy. Prenatal alcohol exposure should be the focus of efforts to improve identification of alcohol use prior to and during pregnancy to improve maternal and child health. Birth Defects Research (Part A) 97:489-496, 2013. © 2013 Wiley Periodicals, Inc.
确定刚果布拉柴维尔地区产前饮酒的患病率，并评估一种适用于该人群的产前筛查工具。
在刚果布拉柴维尔的10家产前保健诊所对3099名妇女进行前瞻性人群筛查，采用单问题筛查法。为了在该人群中验证单问题筛查法，我们再次对其中764名妇女进行筛查，使用T-ACE作为比较研究的金标准。研究结果如下：使用单问题筛查法得出的布拉柴维尔地区自我报告的产前饮酒患病率、饮酒天数估计、每日饮酒量、单次饮酒最多量。我们还估计了单问题筛查法的流行病学性能标准。
接受筛查的3099名妇女分类如下：无风险77%（n = 2384）；有风险3.7%（n = 115）；高风险19.3%（n = 600）。在报告孕期饮酒的妇女中，87.4%报告在任何情况下饮酒4杯或更多。单问题筛查法与T-ACE阳性评分在检测孕期饮酒方面的一致性为94.7%。
在刚果布拉柴维尔接受产前护理的妇女中，23.3%报告在孕期饮酒，其中83%在确认怀孕后仍继续饮酒。产前酒精暴露应成为改善孕期前后酒精使用识别工作的重点，以改善母婴健康。《出生缺陷研究（A部分）》97:489 - 496，2013年。© 2013威利期刊公司。
