Schmitz K F, Hoffmann K, Müller F, Krech T, Scheid A, Adams O, Neumann B, Reifferscheid S, Worth H
Abteilung für Kardiologie, Pneumologie und Angiologie, Universität Düsseldorf.
Pneumologie. 1990 Feb;44 Suppl 1:178-9.
The importance of serological determination procedures for the diagnosis of pathogens was investigated in 207 episodes of pneumonia. The pathogenic organisms were detected in 138 cases; in 40 cases serological analysis helped to establish the diagnosis, while in 11 cases of pneumonia, the diagnosis was possible only with serology. The organisms most commonly found by serological investigations were Cytomegalovirus (n = 10), Aspergillus fumigatus (n = 7), and the influenza B virus (n = 7). Multiple infections, usually triggered by bacterial pathogens, were found in 48% of the cases of pneumonia with serological evidence of pathogens. In 71 episodes of pneumonia, the patients were immunosuppressed; in 11 cases, the causative organism was detected serologically.
在207例肺炎病例中,研究了血清学检测程序对病原体诊断的重要性。138例检测出致病生物;40例中血清学分析有助于确诊,而在11例肺炎病例中,仅靠血清学才能做出诊断。血清学检测最常发现的生物是巨细胞病毒(n = 10)、烟曲霉(n = 7)和乙型流感病毒(n = 7)。在有血清学证据表明存在病原体的肺炎病例中,48%发现有通常由细菌病原体引发的多重感染。在71例肺炎病例中,患者存在免疫抑制;11例中通过血清学检测出了致病生物。