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Tdap vaccine during pregnancy.孕期接种破伤风类毒素、白喉、百日咳联合疫苗
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本文引用的文献

1
Advisory Committee on Immunization Practices (ACIP) recommended immunization schedule for persons aged 0 through 18 years--United States, 2013.美国免疫实践咨询委员会(ACIP)2013年针对0至18岁人群的推荐免疫接种时间表
MMWR Suppl. 2013 Feb 1;62(1):2-8.
2
Waning protection after fifth dose of acellular pertussis vaccine in children.儿童接种五剂无细胞百日咳疫苗后的保护作用减弱。
N Engl J Med. 2012 Sep 13;367(11):1012-9. doi: 10.1056/NEJMoa1200850.
3
The number needed to vaccinate to prevent infant pertussis hospitalization and death through parent cocoon immunization.通过父母疫苗接种预防婴儿百日咳住院和死亡所需的疫苗接种人数。
Clin Infect Dis. 2012 Feb 1;54(3):318-27. doi: 10.1093/cid/cir836. Epub 2011 Dec 8.
4
Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine (Tdap) in pregnant women and persons who have or anticipate having close contact with an infant aged <12 months --- Advisory Committee on Immunization Practices (ACIP), 2011.更新的破伤风类毒素、白喉类毒素和无细胞百日咳疫苗(Tdap)在孕妇和有或预计有密切接触 12 个月以下婴儿的人群中使用建议---免疫实践咨询委员会(ACIP),2011 年。
MMWR Morb Mortal Wkly Rep. 2011 Oct 21;60(41):1424-6.
5
Maternal immunization with tetanus-diphtheria-pertussis vaccine: effect on maternal and neonatal serum antibody levels.母亲接种破伤风白喉无细胞百日咳联合疫苗:对母体和新生儿血清抗体水平的影响。
Am J Obstet Gynecol. 2011 Apr;204(4):334.e1-5. doi: 10.1016/j.ajog.2010.11.024. Epub 2011 Jan 26.
6
Prevention of pertussis, tetanus, and diphtheria among pregnant and postpartum women and their infants recommendations of the Advisory Committee on Immunization Practices (ACIP).孕妇和产后妇女及其婴儿百日咳、破伤风和白喉的预防——免疫实践咨询委员会(ACIP)的建议
MMWR Recomm Rep. 2008 May 30;57(RR-4):1-51.
7
[Vaccination in parents of young infants survey].[针对幼儿父母的疫苗接种调查]
Arch Pediatr. 2007 Dec;14(12):1472-6. doi: 10.1016/j.arcped.2007.09.005. Epub 2007 Oct 29.
8
Preventing tetanus, diphtheria, and pertussis among adults: use of tetanus toxoid, reduced diphtheria toxoid and acellular pertussis vaccine recommendations of the Advisory Committee on Immunization Practices (ACIP) and recommendation of ACIP, supported by the Healthcare Infection Control Practices Advisory Committee (HICPAC), for use of Tdap among health-care personnel.预防成人破伤风、白喉和百日咳:免疫实践咨询委员会(ACIP)关于使用破伤风类毒素、吸附白喉类毒素和无细胞百日咳疫苗的建议,以及在医疗感染控制实践咨询委员会(HICPAC)支持下,ACIP关于医护人员使用破伤风类毒素、低剂量白喉类毒素和无细胞百日咳疫苗(Tdap)的建议。
MMWR Recomm Rep. 2006 Dec 15;55(RR-17):1-37.
9
Prevention and Control of Influenza: recommendations of the Advisory Committee on Immunization Practices (ACIP).流感的预防与控制:免疫实践咨询委员会(ACIP)的建议
MMWR Recomm Rep. 2006 Jul 28;55(RR-10):1-42.
10
Update on adolescent immunization: review of pertussis and the efficacy, safety, and clinical use of vaccines that contain tetanus-diphtheria-acellular pertussis.青少年免疫接种最新情况:百日咳及破伤风-白喉-无细胞百日咳疫苗的疗效、安全性和临床应用综述
J Pediatr Health Care. 2006 Jul-Aug;20(4):229-37. doi: 10.1016/j.pedhc.2005.12.011.

孕妇接种 Tdap 疫苗以减少婴幼儿百日咳感染。

Tdap vaccination during pregnancy to reduce pertussis infection in young infants.

出版信息

Can Fam Physician. 2013 May;59(5):497-8.

PMID:23673584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3653651/
Abstract

QUESTION

What is the basis for the new recommendations to vaccinate pregnant women against pertussis after the first trimester?

ANSWER

There have been outbreaks of epidemic proportions of pertussis, mostly among young infants who have not received sufficient passive immunity from their mothers. This strategy of vaccination during pregnancy aims at stopping these life-threatening epidemics.

摘要

问题

新的建议是在妊娠第一 trimester 后为孕妇接种百日咳疫苗,其依据是什么?

答案

百日咳已经爆发流行,主要发生在未从母亲那里获得足够被动免疫力的婴儿中。这种在妊娠期间接种疫苗的策略旨在阻止这些危及生命的疫情。