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孕妇接种 Tdap 疫苗以减少婴幼儿百日咳感染。

Tdap vaccination during pregnancy to reduce pertussis infection in young infants.

出版信息

Can Fam Physician. 2013 May;59(5):497-8.

Abstract

QUESTION

What is the basis for the new recommendations to vaccinate pregnant women against pertussis after the first trimester?

ANSWER

There have been outbreaks of epidemic proportions of pertussis, mostly among young infants who have not received sufficient passive immunity from their mothers. This strategy of vaccination during pregnancy aims at stopping these life-threatening epidemics.

摘要

问题

新的建议是在妊娠第一 trimester 后为孕妇接种百日咳疫苗,其依据是什么?

答案

百日咳已经爆发流行,主要发生在未从母亲那里获得足够被动免疫力的婴儿中。这种在妊娠期间接种疫苗的策略旨在阻止这些危及生命的疫情。

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本文引用的文献

2
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N Engl J Med. 2012 Sep 13;367(11):1012-9. doi: 10.1056/NEJMoa1200850.
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The number needed to vaccinate to prevent infant pertussis hospitalization and death through parent cocoon immunization.
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Maternal immunization with tetanus-diphtheria-pertussis vaccine: effect on maternal and neonatal serum antibody levels.
Am J Obstet Gynecol. 2011 Apr;204(4):334.e1-5. doi: 10.1016/j.ajog.2010.11.024. Epub 2011 Jan 26.
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