Discher T, Schmitt J, Stark K, Sitte J, Velcovcky H G, Federlin K
Med. Klinik III und Poliklinik der Universität Giessen.
Pneumologie. 1990 Feb;44 Suppl 1:210-2.
The flow-volume curves of 246 patients with dyspnoea on exertion were analysed. In the presence of normal lung volumes and capacities and normal airway resistance, 52% of the patients were found already to have pathologically changed forced expiration figures. In patients with non-bronchogenic disorders, a predominately inspiratory reduction in flow was detected, in particular a reduction in maximum flow. Characteristic findings can be established already in the initial stage of ventilation disorders. Patients with diffuse pulmonary diseases are characterised by a virtually normal PEF, a steep decline in phase II of forced expiration, and a restriction in inspiration. Goitre-associated stenoses with a functional effect are characterised by a reduced expiratory peak flow, homogeneous expiration and reduced inspiratory flow. In patients with bronchial diseases, a functional overdistension can be detected even in the symptom-free stage with the aid of the quotient ITGV % MEF50% VC. In our opinion, the flow-volume curve should therefore be considered an indispensable investigation within the framework of pulmonary function diagnostic evaluation.
对246例劳力性呼吸困难患者的流量-容积曲线进行了分析。在肺容积和容量正常且气道阻力正常的情况下,发现52%的患者已有病理性改变的用力呼气指标。在非支气管源性疾病患者中,检测到主要是吸气流量减少,尤其是最大流量减少。在通气障碍的初始阶段即可确定特征性表现。弥漫性肺部疾病患者的特征是呼气峰值流速基本正常、用力呼气第二阶段急剧下降以及吸气受限。具有功能影响的甲状腺肿相关性狭窄的特征是呼气峰值流量降低、呼气均匀且吸气流量降低。在支气管疾病患者中,即使在无症状阶段,借助ITGV%/MEF50%/VC比值也可检测到功能性肺过度膨胀。因此,我们认为,在肺功能诊断评估框架内,流量-容积曲线应被视为一项不可或缺的检查。