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磷酸钙涂层表面钛种植体的垂直骨传导特性——一项在兔身上的初步研究

Vertical osteoconductive characteristics of titanium implants with calcium-phosphate-coated surfaces - a pilot study in rabbits.

作者信息

Schiegnitz Eik, Palarie Victor, Nacu Viorel, Al-Nawas Bilal, Kämmerer Peer Wolfgang

机构信息

Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; State Medical and Pharmaceutical University "Nicolae Testemitanu", Chisinau, Moldova, Clinic for Oral & Maxillofacial Surgery, Chisinau, Moldova; State Medical and Pharmaceutical University "Nicolae Testemitanu," Chisinau, Moldova, Clinic for Oral & Maxillofacial Surgery, Chisinau, Moldova; Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany; Department of Oral and Maxillofacial Surgery, Plastic Surgery, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany.

出版信息

Clin Implant Dent Relat Res. 2014 Apr;16(2):194-201. doi: 10.1111/j.1708-8208.2012.00469.x.

Abstract

INTRODUCTION

Osteoconductive characteristics of different implant surface coatings are in the focus of current interest. The aim of the present study was to compare the vertical osteoconductivity at the implant shoulder of supracrestal inserted calcium-phosphate coated implants (SLA-CaP) with conventional sand-blasted/acid-etched (SLA) implants in a rabbit model.

MATERIALS AND METHODS

SLA-CaP and SLA implants were inserted bilaterally in the mandible of four rabbits in a split-mouth design. The implants were placed 2 mm supracrestal. After 3 weeks, at the left and right implant shoulder, the percentage of linear bone fill (PLF) as well as bone-implant contact (BIC-D) were determined.

RESULTS

After 3 weeks, newly formed woven bone could be found at the shoulder of the most of both surface-treated implants (75%). PLF was significantly higher in SLA-CaP implants (11.2% vs. 46.5%; n = 8, p = .008). BIC-D was significantly increased in the SLA-CaP implants (13.0% vs. 71.4%; n = 8, p < .001) as well.

CONCLUSION

The results of this study show for the first time that calcium-phosphate coated surfaces on supracrestal inserted implants have vertical osteoconductive characteristics and increase the bone-implant contact at the implant shoulder significantly in a rabbit model. In clinical long-term settings, these implants may contribute to a better vertical bone height.

摘要

引言

不同种植体表面涂层的骨传导特性是当前研究的热点。本研究的目的是在兔模型中比较龈上植入的磷酸钙涂层种植体(SLA-CaP)与传统喷砂/酸蚀(SLA)种植体在种植体肩部的垂直骨传导性。

材料与方法

采用双侧分口设计,将SLA-CaP和SLA种植体植入4只兔子的下颌骨。种植体龈上植入2mm。3周后,测定左右种植体肩部的线性骨填充百分比(PLF)以及骨-种植体接触率(BIC-D)。

结果

3周后,在大多数两种表面处理的种植体肩部(75%)均可发现新形成的编织骨。SLA-CaP种植体的PLF显著更高(11.2%对46.5%;n = 8,p = 0.008)。SLA-CaP种植体的BIC-D也显著增加(13.0%对71.4%;n = 8,p < 0.001)。

结论

本研究结果首次表明,龈上植入的种植体上的磷酸钙涂层表面具有垂直骨传导特性,并在兔模型中显著增加了种植体肩部的骨-种植体接触。在临床长期应用中,这些种植体可能有助于获得更好的垂直骨高度。

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