Department of Chemistry, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, Fudan University, Shanghai 200433, People's Republic of China.
Chem Commun (Camb). 2013 Jun 21;49(49):5589-91. doi: 10.1039/c3cc42534g.
The first example of rare earth metal-catalyzed cycloaddition of terminal alkynes to azides resulting in the formation of 1,5-disubstituted 1,2,3-triazoles is described. Preliminary studies revealed that the present cycloaddition shows unprecedented mechanistic features involving a tandem anionic cascade cyclization and anti-addition across the C≡C triple bond.
首例稀土金属催化的末端炔烃与叠氮化物的环加成反应，生成 1,5-取代的 1,2,3-三唑，本文对此进行了描述。初步研究表明，本环加成反应具有前所未有的反应机理特征，涉及串联的阴离子级联环化和反式加成到 C≡C 三键。
