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支气管哮喘患者的睡眠障碍

Sleep disorders in patients with bronchial asthma.

作者信息

Cukic Vesna, Lovre Vladimir, Dragisic Dejan

机构信息

Clinic for pulmonary diseases and tuberculosis "Podhrastovi", Clinical center, University of Sarajevo, Bosnia and Herzegovina.

出版信息

Mater Sociomed. 2011;23(4):235-7. doi: 10.5455/msm.2011.23.235-237.

Abstract

Respiratory disturbances during sleep are recognized as extremely common disorders with important clinical consequences. Breathing disorders during sleep can result in broad range of clinical manifestations, the most prevalent of which are unrefreshing sleep, daytime sleepiness and fatigue, and cognitive impairmant. There is also evidence that respiratory-related sleep disturbances can contribute to several common cardiovascular and metabolic disorders, including systemic hypertension, cardiac dysfunction, and insulin-resistance. Correlations are found between asthma-related symptoms and sleep disturbances. Difficulties inducing sleep, sleep fragmentation on polysomnography, early morning awakenings and daytime sleepiness are more common in asthmatics compared with subjects without asthma. The "morning deep" in asthma is relevant for the characterization of asthma severity, and impact drugs' choices. Sleep and night control of asthma could be relevant to evaluate disease's control. Appropriate asthma control recovering is guarantor for better sleep quality in these patients and less clinical consequences of respiratory disturbances during sleep.

摘要

睡眠期间的呼吸障碍被认为是极为常见的疾病,具有重要的临床后果。睡眠期间的呼吸障碍可导致广泛的临床表现,其中最常见的是睡眠无恢复感、日间嗜睡和疲劳以及认知障碍。也有证据表明,与呼吸相关的睡眠障碍可导致多种常见的心血管和代谢紊乱,包括系统性高血压、心脏功能障碍和胰岛素抵抗。在哮喘相关症状与睡眠障碍之间发现了相关性。与无哮喘的受试者相比,哮喘患者更常见入睡困难、多导睡眠图显示的睡眠片段化、清晨觉醒和日间嗜睡。哮喘中的“晨重”与哮喘严重程度的特征以及药物选择的影响有关。哮喘的睡眠和夜间控制可能与评估疾病控制情况有关。适当恢复哮喘控制是保证这些患者有更好睡眠质量以及减少睡眠期间呼吸障碍临床后果的关键。

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