Department of Pediatrics, New York University School of Medicine and Bellevue Hospital Center, New York, NY 10016, USA.
Acad Pediatr. 2013 May-Jun;13(3):229-35. doi: 10.1016/j.acap.2013.01.004. Epub 2013 Jan 11.
Parent administration of multiple medications with overlapping active ingredients places children at risk for overdose. We sought to examine how parents use active ingredient information as part of the process of selecting a cough/cold medication for their child and how health literacy plays a role.
Experimental study of parents of children presenting for care in an urban public hospital pediatric clinic. Parents were asked to determine which of 3 cough/cold medications could be given to relieve a child's cold symptoms, as part of a scenario in which they had already given a dose of acetaminophen; only 1 did not contain acetaminophen. Primary dependent variable: correct selection of cough/cold medication by using active ingredient as the rationale for choice. Primary independent variable: parent health literacy (Newest Vital Sign test).
Of 297 parents, 79.2% had low health literacy (Newest Vital Sign score 0-3); 35.4% correctly chose the cough/cold medication that did not contain acetaminophen. The proportion of those who made the correct choice was no different than expected from chance alone (Goodness of fit test; χ(2) = 2.1, P = .3). Only 7.7% chose the correct medication and used active ingredient as the rationale. Those with adequate literacy skills were more likely to have selected the correct medication and rationale (25.8% vs 3.0% (P = .001); adjusted odds ratio 11.1 (95% confidence interval 3.6-33.7), after we adjusted for sociodemographics, including English proficiency and education.
Many parents, especially those with low health literacy, do not use active ingredient information as part of decision-making related to administering multiple medications.
父母给孩子同时服用多种含有相同活性成分的药物会使孩子面临用药过量的风险。本研究旨在考察父母在为孩子选择咳嗽/感冒药时如何使用活性成分信息,以及健康素养在其中发挥的作用。
在一家城市公立医院儿科诊所就诊的儿童的父母参与了这项实验性研究。研究人员向父母提出了一个场景问题,即他们已经给孩子服用了一剂对乙酰氨基酚,现在可以给孩子服用哪种咳嗽/感冒药来缓解孩子的感冒症状,要求父母从 3 种咳嗽/感冒药中选择 1 种。只有 1 种不含对乙酰氨基酚。主要因变量:父母根据活性成分选择咳嗽/感冒药的正确性。主要自变量:父母的健康素养(最新生命体征测试)。
在 297 位父母中,79.2%的父母健康素养较低(最新生命体征评分 0-3);35.4%的父母正确选择了不含对乙酰氨基酚的咳嗽/感冒药。正确选择药物的比例与随机选择的比例没有差异(拟合优度检验;χ²=2.1,P=.3)。只有 7.7%的父母选择了正确的药物,并将活性成分作为选择的依据。有足够读写能力的父母更有可能选择正确的药物和依据(25.8%比 3.0%(P=.001);调整后的优势比 11.1(95%置信区间 3.6-33.7),我们调整了社会人口统计学因素,包括英语熟练程度和教育程度)。
许多父母,尤其是健康素养较低的父母,在给孩子服用多种药物时并没有将活性成分信息作为决策的一部分。