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基于硅光电倍增管的 PET 模块探测器模拟电荷多路复用方案的研究。

Investigation of analog charge multiplexing schemes for SiPM based PET block detectors.

机构信息

School of Biomedical Engineering, McMaster University, Hamilton, Ontario, Canada.

出版信息

Phys Med Biol. 2013 Jun 7;58(11):3943-64. doi: 10.1088/0031-9155/58/11/3943. Epub 2013 May 16.

DOI:10.1088/0031-9155/58/11/3943
PMID:23680653
Abstract

Reducing the number of output channels in pixelated positron emission tomography (PET) detectors is an effective way to minimize cost and complexity while minimizing the impact on detector performance. This paper compares the system performance of two multiplexing schemes by using both simulation and experimental studies, with respect to spatial, time and energy resolutions. Simulations were performed using the SPICE environment to investigate differences in resulting flood histograms and rising edge slopes. Experiments were performed using lutetium-yttrium oxyorthosilicate (LYSO) crystals coupled to a SensL ArraySL-4 silicon photomultiplier (SiPM) connected to interchangeable circuit boards containing the two multiplexing schemes of interest. Three crystal configurations were tested: a single crystal element (3×3×20 mm(3)), 2×2 array (crystal pitch: 2×2) and 6×6 array (crystal pitch: 2.1×2.1×20 mm(3)). Good agreement was found between the simulations and experiment results. It is found that the capacitive multiplexing is able to achieve an improved time resolution of good uniformity (average of 1.11 ± 0.01 ns and 1.90 ± 0.03 ns for the arrays, respectively) and crystal separation, compared to the resistive multiplexing (average of 1.95 ± 0.03 ns and 3.33 ± 0.10 ns). On the other hand, the resistive multiplexing demonstrates slightly improved energy resolution (11 ± 0.1% and 22 ± 0.6%, compared to 12 ± 0.1% and 24 ± 0.4% for the capacitive array), which is believed to be caused by the RC circuit formed between the splitting capacitors and the input impedance of amplifiers. The relevancy of this work to the PET block detector design using SiPM arrays is also discussed, including light sharing, edge compression and gain variation among SiPM pixels.

摘要

在像素化正电子发射断层扫描(PET)探测器中减少输出通道的数量是一种有效的方法,可以在最小化成本和复杂性的同时,最小化对探测器性能的影响。本文通过仿真和实验研究比较了两种复用方案的系统性能,分别从空间、时间和能量分辨率方面进行了评估。使用 SPICE 环境进行仿真,以研究不同的洪水直方图和上升沿斜率。实验使用掺镥硅酸钇(LYSO)晶体与 SensL ArraySL-4 硅光电倍增管(SiPM)耦合进行,SiPM 连接到包含两种复用方案的可互换电路板。测试了三种晶体配置:单个晶体元件(3×3×20mm3)、2×2 阵列(晶体间距:2×2)和 6×6 阵列(晶体间距:2.1×2.1×20mm3)。仿真和实验结果吻合良好。发现与电阻性复用相比,电容性复用能够实现更好的时间分辨率和均匀性(分别为 1.11±0.01ns 和 1.90±0.03ns,以及 1.11±0.01ns 和 1.90±0.03ns)和晶体分离。另一方面,电阻性复用表现出稍高的能量分辨率(11±0.1%和 22±0.6%,而电容性阵列为 12±0.1%和 24±0.4%),这被认为是由于分压器和放大器输入阻抗之间形成的 RC 电路所致。还讨论了这项工作与使用 SiPM 阵列的 PET 块探测器设计的相关性,包括光共享、边缘压缩和 SiPM 像素之间的增益变化。

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