Xie Jiahao, Wang Haibo, Cherry Simon R, Du Junwei
Department of Biomedical Engineering, University of California at Davis, Davis, CA 95616 USA.
IEEE Trans Radiat Plasma Med Sci. 2024 May;8(5):493-500. doi: 10.1109/trpms.2024.3381865. Epub 2024 Mar 26.
Almost all high spatial resolution positron emission tomography (PET) detectors based on pixelated scintillator arrays utilize crystal arrays with smaller pitches than photodetector arrays, leading to challenges in resolving edge crystals. To address this issue, this paper introduces a novel multi-resolution silicon photomultiplier (SiPM) array design aimed at decreasing the number of readout channels required while maintaining the crystal resolvability of the detector, especially for edge crystals. The performance of a pseudo 9 × 9 multi-resolution SiPM array, consisting of 6.47 × 6.47 mm, 6.47 × 3.07 mm, and 3.07 × 3.07 mm SiPMs, was compared to those of a pseudo 8 × 8 SiPM array with a 6.8 mm pitch, and a 16 × 16 SiPM array with a 3.4 mm pitch using a 36 × 36 LYSO array with a pitch of 1.5 mm. The large-size pseudo SiPMs were implemented by digitally grouping multiple 3.07 × 3.07 mm SiPMs. The flood histograms show that the edge crystal resolvability of the pseudo 9 × 9 multi-resolution SiPM array is comparable to that of the 16 × 16 SiPM array and is significantly better than that of the 8 × 8 SiPM array.
几乎所有基于像素化闪烁体阵列的高空间分辨率正电子发射断层扫描(PET)探测器都采用了间距比光电探测器阵列更小的晶体阵列,这给分辨边缘晶体带来了挑战。为了解决这个问题,本文引入了一种新颖的多分辨率硅光电倍增管(SiPM)阵列设计,旨在减少所需的读出通道数量,同时保持探测器对晶体的分辨能力,特别是对于边缘晶体的分辨能力。将一个由6.47×6.47毫米、6.47×3.07毫米和3.07×3.07毫米的SiPM组成的伪9×9多分辨率SiPM阵列的性能,与一个间距为6.8毫米的伪8×8 SiPM阵列以及一个间距为3.4毫米的16×16 SiPM阵列的性能进行了比较,所使用的晶体阵列为间距1.5毫米的36×36硅酸钇镥(LYSO)阵列。大型伪SiPM是通过对多个3.07×3.07毫米的SiPM进行数字分组来实现的。泛光直方图显示,伪9×9多分辨率SiPM阵列对边缘晶体的分辨能力与16×16 SiPM阵列相当,且明显优于8×8 SiPM阵列。