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Ketogenic diets and pain.生酮饮食与疼痛。
J Child Neurol. 2013 Aug;28(8):993-1001. doi: 10.1177/0883073813487595. Epub 2013 May 16.
2
Ketogenic diets and thermal pain: dissociation of hypoalgesia, elevated ketones, and lowered glucose in rats.生酮饮食与热痛：大鼠镇痛作用降低、酮体升高和血糖降低的分离现象。
J Pain. 2013 May;14(5):467-74. doi: 10.1016/j.jpain.2012.12.015. Epub 2013 Mar 15.
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Reduced pain and inflammation in juvenile and adult rats fed a ketogenic diet.给予生酮饮食的幼年和成年大鼠可减轻疼痛和炎症。
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Ketogenic diet effects on inflammatory allodynia and ongoing pain in rodents.生酮饮食对啮齿动物炎症性触诱发痛和持续性疼痛的影响。
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MCT-modified ketogenic diet as an adjunct to standard treatment regimen could alleviate clinical symptoms in women with endometriosis.中链甘油三酯改良生酮饮食作为标准治疗方案的辅助手段，可缓解子宫内膜异位症女性的临床症状。
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本文引用的文献

1
Ketogenic diets and thermal pain: dissociation of hypoalgesia, elevated ketones, and lowered glucose in rats.生酮饮食与热痛：大鼠镇痛作用降低、酮体升高和血糖降低的分离现象。
J Pain. 2013 May;14(5):467-74. doi: 10.1016/j.jpain.2012.12.015. Epub 2013 Mar 15.
2
Genomic responses in mouse models poorly mimic human inflammatory diseases.小鼠模型中的基因组反应与人类炎症性疾病的反应相差很大。
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12. doi: 10.1073/pnas.1222878110. Epub 2013 Feb 11.
3
High-intensity swimming exercise reduces neuropathic pain in an animal model of complex regional pain syndrome type I: evidence for a role of the adenosinergic system.高强度游泳运动减轻复杂性区域疼痛综合征 I 型动物模型中的神经性疼痛：涉及腺苷能系统的作用证据。
Neuroscience. 2013 Mar 27;234:69-76. doi: 10.1016/j.neuroscience.2012.12.042. Epub 2013 Jan 3.
4
Traditional acupuncture triggers a local increase in adenosine in human subjects.传统针灸会引起人体局部腺苷的增加。
J Pain. 2012 Dec;13(12):1215-23. doi: 10.1016/j.jpain.2012.09.012.
5
Seizures in Alzheimer disease: clinical and epidemiological data.阿尔茨海默病中的癫痫发作：临床和流行病学数据。
Epilepsy Curr. 2012 Sep;12(5):184-7. doi: 10.5698/1535-7511-12.5.184.
6
Obesity and metabolic syndrome and functional and structural brain impairments in adolescence.青少年肥胖、代谢综合征与大脑功能和结构损伤
Pediatrics. 2012 Oct;130(4):e856-64. doi: 10.1542/peds.2012-0324. Epub 2012 Sep 3.
7
Low-carbohydrate ketogenic diets, glucose homeostasis, and nonalcoholic fatty liver disease.低碳水化合物生酮饮食、葡萄糖稳态和非酒精性脂肪肝病。
Curr Opin Clin Nutr Metab Care. 2012 Jul;15(4):374-80. doi: 10.1097/MCO.0b013e3283547157.
8
Inflammation-mediated memory dysfunction and effects of a ketogenic diet in a murine model of multiple sclerosis.炎症介导的记忆功能障碍及生酮饮食对多发性硬化症小鼠模型的影响。
PLoS One. 2012;7(5):e35476. doi: 10.1371/journal.pone.0035476. Epub 2012 May 2.
9
The ketogenic diet as a treatment paradigm for diverse neurological disorders.生酮饮食作为多种神经系统疾病的治疗模式。
Front Pharmacol. 2012 Apr 9;3:59. doi: 10.3389/fphar.2012.00059. eCollection 2012.
10
The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy.神经系统与代谢失调：越来越多的证据表明生酮饮食疗法与之相关。
Front Neurosci. 2012 Mar 26;6:33. doi: 10.3389/fnins.2012.00033. eCollection 2012.

生酮饮食与疼痛。

Ketogenic diets and pain.

作者信息

Masino Susan A, Ruskin David N

机构信息

Neuroscience Program and Department of Psychology, Trinity College, Hartford, CT 06106, USA.

出版信息

J Child Neurol. 2013 Aug;28(8):993-1001. doi: 10.1177/0883073813487595. Epub 2013 May 16.

DOI:10.1177/0883073813487595
PMID:23680946
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4124736/
Abstract

Ketogenic diets are well established as a successful anticonvulsant therapy. Based on overlap between mechanisms postulated to underlie pain and inflammation, and mechanisms postulated to underlie therapeutic effects of ketogenic diets, recent studies have explored the ability for ketogenic diets to reduce pain. Here we review clinical and basic research thus far exploring the impact of a ketogenic diet on thermal pain, inflammation, and neuropathic pain.

摘要

生酮饮食作为一种成功的抗惊厥疗法已被广泛认可。基于推测的疼痛和炎症潜在机制与推测的生酮饮食治疗效果潜在机制之间的重叠，最近的研究探讨了生酮饮食减轻疼痛的能力。在此，我们综述了迄今为止探索生酮饮食对热痛、炎症和神经性疼痛影响的临床和基础研究。