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41周以上妊娠的引产与期待治疗

Induction of labor versus expectant management for pregnancies beyond 41 weeks.

作者信息

Daskalakis George, Zacharakis Dimitrios, Simou Maria, Pappa Peny, Detorakis Stelios, Mesogitis Spyros, Antsaklis Aris

机构信息

1st Department of Obstetrics and Gynecology, "Alexandra" Maternity Hospital, Athens University , Athens , Greece.

出版信息

J Matern Fetal Neonatal Med. 2014 Jan;27(2):173-6. doi: 10.3109/14767058.2013.806892. Epub 2013 Jun 20.

Abstract

OBJECTIVE

To compare the outcome following labor induction at 41 + 1 weeks of gestation and after expectant management and selective induction at 42 completed weeks.

METHOD

A retrospective analysis of post-term pregnancies in a 2-year period. In the induction group, women at 41 + 1 weeks of gestation received 3 mg prostaglandin E2 (dinoprostone) in the posterior fornix, repeating the dose 6 h later. Women with a Bishop score >6 had artificial rupture of the membranes. In the expectant management group, women at more than 41 weeks gestation were checked every 2 days in the hospital. In case of abnormalities either in the fetal heart rate evaluation or in the biophysical profile, labor was induced. Labor was also induced in all cases that pregnancy exceeded 42 + 1 gestational weeks.

RESULTS

A total of 438 women who met the inclusion criteria were included in the study. In all, 211 comprised the induction group, while the expectant management group consisted of 227 women. The cesarean delivery rate in the induction group was 36.5% compared to 34.4% in the expectant management group, whereas the operative vaginal delivery rate was 11.4 and 9.2% in the two groups, respectively. The vast majority of women in the expectant management group (74%) had a spontaneous onset of labor.

CONCLUSION

The perinatal outcome does not differ following a policy of routine labor induction in comparison to expectant management in pregnancies beyond 41 weeks.

摘要

目的

比较妊娠41+1周引产与42足周期待治疗及选择性引产的结局。

方法

对两年内过期妊娠进行回顾性分析。引产组中,妊娠41+1周的妇女在后穹窿给予3mg前列腺素E2(地诺前列酮),6小时后重复给药。Bishop评分>6的妇女行人工破膜。期待治疗组中,妊娠超过41周的妇女在医院每2天检查一次。若胎儿心率评估或生物物理评分出现异常,则引产。妊娠超过42+1孕周的所有病例也均引产。

结果

共有438名符合纳入标准的妇女纳入研究。其中,211名组成引产组,期待治疗组由227名妇女组成。引产组剖宫产率为36.5%,期待治疗组为34.4%,而两组的阴道手术助产率分别为11.4%和9.2%。期待治疗组绝大多数妇女(74%)自然发动分娩。

结论

与41周以上妊娠的期待治疗相比,常规引产策略下的围产期结局并无差异。

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