Medicine Department, School of Medicine, Universidad Nacional de Colombia, Bogotá, Colombia.
Braz J Infect Dis. 2013 May-Jun;17(3):346-52. doi: 10.1016/j.bjid.2012.10.022. Epub 2013 May 14.
The aim of this study was to describe the most frequently found bacterial microorganisms in bloodstream isolates taken from patients in intensive care units in Colombia and their resistance profiles.
This was a multicentre descriptive observational study that was carried out between January 2001 and June 2008 with laboratory data from 33 participating hospitals in a surveillance network.
The most frequently found microorganisms were coagulase-negative Staphylococci 39.6%, Staphylococcus aureus 12.3%, Klebsiella pneumoniae 8.2%, Escherichia coli 5.7%, Acinetobacter baumannii, 4.0% and Pseudomonas aeruginosa 3.8%. Coagulase-negative Staphylococci registered greater than 70% oxacillin resistance rate. S. aureus presented a change in its multiresistance profile during the years of follow-up. There was a trend towards a lower resistance rate among E. coli and K. pneumoniae isolates during the study period while A. baumannii carbapenem resistance rate exceeded 50%.
There has been a change in the frequency of species being isolated with a higher frequency of enterobacteriaceae compared to Gram-positive microorganisms, in general with a high resistance rate.
本研究旨在描述从哥伦比亚重症监护病房患者血培养分离株中最常发现的细菌微生物及其耐药谱。
这是一项多中心描述性观察研究，于 2001 年 1 月至 2008 年 6 月进行，涉及监测网络中 33 家参与医院的实验室数据。
最常发现的微生物是凝固酶阴性葡萄球菌 39.6%，金黄色葡萄球菌 12.3%，肺炎克雷伯菌 8.2%，大肠埃希菌 5.7%，鲍曼不动杆菌 4.0%和铜绿假单胞菌 3.8%。凝固酶阴性葡萄球菌的苯唑西林耐药率超过 70%。金黄色葡萄球菌在随访期间其多耐药谱发生了变化。在研究期间，大肠埃希菌和肺炎克雷伯菌分离株的耐药率呈下降趋势，而鲍曼不动杆菌碳青霉烯类耐药率超过 50%。
与革兰氏阳性微生物相比，分离物种的频率发生了变化，肠杆菌科的频率更高，一般耐药率也更高。
