Northern Hospital of Surry County, Mount Airy, NC, USA.
Adv Skin Wound Care. 2013 Jun;26(6):259-62. doi: 10.1097/01.ASW.0000431084.85141.d1.
: The purpose of this investigation was to determine the effectiveness of silver sulfadiazine as compared with Aquacel Ag in patients with superficial partial-thickness burns.
: Twenty-four subjects who sustained superficial partial-thickness burns who were between the ages of 19 and 53 years with time of injury from 0 to 4 days were randomly assigned into a control group (silver sulfadiazine) and experimental group (Aquacel Ag; ConvaTec, Skillman, New Jersey). Wound measurements were assessed at the time of the initial examination and every 4 days afterward until the area was re-epithelialized 100%. To ensure objectivity, the burn area was measured digitally with the software program by Aspyra (Aspyra LLC; Blue Springs, Missouri) to prevent discrepancies in wound measurements.
: Significant differences between the silver sulfadiazine and Aquacel Ag group were noted in pain (silver sulfadiazine: 4.70 ± 2.22, Aquacel Ag: 2.92 ± 1.12) and the number of treatments (silver sulfadiazine: 10.27 ± 7.46, Aquacel Ag: 4.10 ± 1.38).
: Utilization of Aquacel Ag in superficial-partial thickness burns could lead to a decrease in the number of treatments required to re-epithelialize burns 100% with less pain as compared with silver sulfadiazine.
本研究旨在比较磺胺嘧啶银与 Aquacel Ag 在浅Ⅱ度烧伤患者中的疗效。
将 24 例年龄在 19 至 53 岁之间、伤后时间在 0 至 4 天之间的浅Ⅱ度烧伤患者随机分为对照组(磺胺嘧啶银)和实验组(Aquacel Ag;康维德,新泽西州斯克里尔曼)。在初次检查时和此后每 4 天测量一次伤口,直到 100%的创面完全上皮化。为了确保客观性,使用 Aspyra 软件程序(Aspyra LLC;密苏里州布卢斯普林斯)对烧伤面积进行数字化测量,以防止伤口测量的差异。
磺胺嘧啶银组和 Aquacel Ag 组在疼痛(磺胺嘧啶银:4.70±2.22,Aquacel Ag:2.92±1.12)和治疗次数(磺胺嘧啶银:10.27±7.46,Aquacel Ag:4.10±1.38)方面存在显著差异。
与磺胺嘧啶银相比,Aquacel Ag 在浅Ⅱ度烧伤中的应用可减少 100%上皮化所需的治疗次数,减轻疼痛。