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Aquacel(®) Ag 敷料与 Acticoat™ 敷料在部分厚度烧伤中的比较:100 例患者前瞻性、随机、对照研究。第 1 部分:烧伤创面愈合。

Aquacel(®) Ag dressing versus Acticoat™ dressing in partial thickness burns: a prospective, randomized, controlled study in 100 patients. Part 1: burn wound healing.

机构信息

Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium.

Department of Plastic and Reconstructive Surgery, Wound Healing and Tissue Engineering Unit, Gent University Hospital, Gent, Belgium.

出版信息

Burns. 2014 May;40(3):416-27. doi: 10.1016/j.burns.2013.07.008. Epub 2013 Sep 14.

Abstract

INTRODUCTION

Studies comparing contemporary silver dressings in burns are scarce.

METHODS

In a prospective, randomized, controlled study, counting 50 patients/research group, we compared two frequently used silver dressings, Acticoat™ and Aquacel(®) Ag, in the management of partial thickness burns with a predicted healing time between 7 and 21 days as assessed by laser Doppler imaging between 48 and 72h after burn. Variables investigated were related to baseline research group characteristics, wound healing, bacteriology, economics, nurse, and patient experience.

RESULTS

Both research groups were comparably composed taking into account gender, age and burn characteristics. Similar results were obtained as to healing time and bacterial control with both silver dressings. A statistically significant difference in favor of the Aquacel(®) Ag dressing was found for average ease of use (p<0.001), average ease of application (p=0.001), patient pain (p<0.001), patient comfort with the dressing (p=0.017), silver staining (p<0.001), and cost effectiveness (p<0.001).

CONCLUSION

Both silver dressings resulted in comparable healing times and bacterial control but the Aquacel(®) Ag dressing significantly increased comfort for patients as well as nurses and was significantly more cost-effective than the Acticoat™ dressing for the given indication.

摘要

引言

比较烧伤中当代银敷料的研究很少。

方法

在一项前瞻性、随机、对照研究中,我们对两种常用的银敷料(Acticoat™和Aquacel(®) Ag)进行了比较,研究对象为预计愈合时间在 7 至 21 天之间的部分厚度烧伤患者,共 50 例/研究组,采用激光多普勒成像技术在烧伤后 48 至 72 小时进行评估。调查的变量与基线研究组特征、伤口愈合、细菌学、经济学、护士和患者体验有关。

结果

考虑到性别、年龄和烧伤特征,两组研究组的构成相似。两种银敷料的愈合时间和细菌控制结果相似。在平均易用性(p<0.001)、平均易用性(p=0.001)、患者疼痛(p<0.001)、患者对敷料的舒适度(p=0.017)、银染色(p<0.001)和成本效益(p<0.001)方面,Aquacel(®) Ag 敷料均具有统计学优势。

结论

两种银敷料的愈合时间和细菌控制结果相似,但 Aquacel(®) Ag 敷料显著提高了患者和护士的舒适度,与 Acticoat™ 敷料相比,在给定适应症下具有更高的成本效益。

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