Department of Virology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India,
Arch Virol. 2013 Nov;158(11):2359-63. doi: 10.1007/s00705-013-1717-4. Epub 2013 May 18.
Mumps is a vaccine-preventable disease that usually occurs as a self-limiting parotitis, but it can also lead to several life-threatening complications, including pancreatitis, meningitis, and encephalitis. The molecular epidemiology of the virus is poorly understood. The present study describes an outbreak of mumps virus infection in Punjab, India. The etiology was confirmed by serology and RNA detection to be mumps virus in 72 % of the cases and 50 % of contacts. This study, for the first time, revealed the mumps virus genotypes circulating in the Indian subcontinent as subtype G2 of genotype G.
腮腺炎是一种可通过疫苗预防的疾病,通常表现为自限性腮腺炎,但它也可导致几种危及生命的并发症,包括胰腺炎、脑膜炎和脑炎。该病毒的分子流行病学尚未完全清楚。本研究描述了印度旁遮普邦的腮腺炎病毒感染暴发。通过血清学和 RNA 检测,在 72%的病例和 50%的接触者中证实病因是腮腺炎病毒。本研究首次揭示了在印度次大陆流行的腮腺炎病毒基因型为 G 基因型的 G2 亚型。