Department of Medical Physics and Biomedical Engineering, Tehran University of Medical Sciences, Tehran, Iran.
Eur Rev Med Pharmacol Sci. 2013 May;17(9):1141-8.
Nanotechnology is developed to convert research, prevention, and treatment of cancer through the novel diagnostic imaging techniques and therapies. In particular, the imaging nanotechnology has gained substantial momentum in recent years. The main progress in nanotechnology has led to the production of novel fluorescent probes named quantum dots (QDs). Quantum dots develop a revolution in the molecular tagging processes within research, in vivo and in vitro studies. Due to unique physical and chemical features of QD probes, new possible techniques of early cancer detection and therapeutic management are being surveyed. Quantum dots have also dissolved many of the restrictions of organic fluorophores and are a talented option as a research tool.
This review addresses on the present status of research, preclinical applications and also future visions of quantum dots.
纳米技术的发展旨在通过新型诊断成像技术和疗法来推动癌症的研究、预防和治疗。特别是，成像纳米技术近年来得到了迅猛发展。纳米技术的主要进展导致了新型荧光探针的产生，这些探针被命名为量子点（Quantum Dots，QDs）。量子点在研究、体内和体外研究中的分子标记过程中引发了一场革命。由于 QD 探针具有独特的物理和化学特性，因此正在探索新的早期癌症检测和治疗管理技术。量子点还解决了有机荧光团的许多限制，是一种很有前途的研究工具。
本文综述了量子点的研究现状、临床前应用和未来展望。
