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量子点在预防肿瘤学中的应用。

Applications of Quantum Dots in Preventive Oncology.

机构信息

Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.

Department of Biotechnology, National Institute of Technology, Durgapur, West Bengal, India.

出版信息

Asian Pac J Cancer Prev. 2024 Mar 1;25(3):747-756. doi: 10.31557/APJCP.2024.25.3.747.


DOI:10.31557/APJCP.2024.25.3.747
PMID:38546057
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11152399/
Abstract

QDs are semiconductor nanocrystalline materials with distinct optical and electronic characteristics due to their microscopic size and quantum mechanical properties. They are often composed of materials such as cadmium selenide (CdSe), cadmium telluride (CdTe), or indium phosphide (InP) and are typically in the size range of 2 to 10 nanometers in diameter. These tiny particles are used in various scientific and technological applications. Some key characteristics and applications of quantum dots are size-dependent Optical Properties with tunable emission. The color of light emitted by quantum dots highly depends on their size. Smaller QDs emit blue or green light, while larger ones emit red or near-infrared light. This tunability makes them valuable in various applications, especially in molecular medicine and oncology research. Quantum dots can exhibit a high quantum yield, meaning they efficiently emit light when excited, making them excellent fluorescent probes for non-invasive imaging. This review discusses the applications of QDs and their role in biomedical research and patient care, focusing on non-invasive imaging and preventive oncology.

摘要

量子点是具有独特光学和电子特性的半导体纳米晶材料,这归因于其微观尺寸和量子力学性质。它们通常由碲化镉(CdTe)、硒化镉(CdSe)或磷化铟(InP)等材料组成,其直径通常在 2 到 10 纳米之间。这些微小的粒子被应用于各种科学和技术领域。量子点的一些关键特性和应用包括:尺寸依赖性光学性质和可调谐发射。量子点发射的光的颜色高度依赖于其尺寸。较小的量子点发射蓝光或绿光,而较大的量子点发射红光或近红外光。这种可调谐性使它们在各种应用中非常有价值,尤其是在分子医学和肿瘤学研究中。量子点可以表现出高量子产率,这意味着它们在被激发时能够有效地发射光,因此它们是用于非侵入性成像的极好的荧光探针。本综述讨论了量子点的应用及其在生物医学研究和患者护理中的作用,重点介绍了非侵入性成像和预防肿瘤学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/d9f8fe660eee/APJCP-25-747-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/28b64c72b7d8/APJCP-25-747-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/553b521c78b8/APJCP-25-747-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/47990eaa2257/APJCP-25-747-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/d9f8fe660eee/APJCP-25-747-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/28b64c72b7d8/APJCP-25-747-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/553b521c78b8/APJCP-25-747-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/47990eaa2257/APJCP-25-747-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b2bf/11152399/d9f8fe660eee/APJCP-25-747-g004.jpg

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本文引用的文献

[1]
Synthesis and characterization of chitosan/carbon quantum dots/FeO nanocomposite comprising curcumin for targeted drug delivery in breast cancer therapy.

Int J Biol Macromol. 2023-9-30

[2]
[Bionic optic nerve based on perovskite (CsPbBr ) quantum-dots].

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2023-6-25

[3]
Silica quantum dots; an optical nanosensing approach for trace detection of pesticides in environmental and biological samples.

Environ Res. 2023-8-15

[4]
Encapsulation of Cadmium-Free InP/ZnSe/ZnS Quantum Dots in Poly(LMA-co-EGDMA) Microparticles via Co-flow Droplet Microfluidics.

Small Methods. 2023-7

[5]
Biomimetic graphene oxide quantum dots nanoparticles targeted photothermal-chemotherapy for gastric cancer.

J Drug Target. 2023-3

[6]
Nanotechnology for colorectal cancer detection and treatment.

World J Gastroenterol. 2022-12-14

[7]
Organic and quantum dot hybrid photodetectors: towards full-band and fast detection.

Chem Commun (Camb). 2023-1-3

[8]
The DNA damage potential of quantum dots: Toxicity, mechanism and challenge.

Environ Pollut. 2023-1-15

[9]
Quantum Dots and Their Interaction with Biological Systems.

Int J Mol Sci. 2022-9-15

[10]
The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections.

Pharmaceuticals (Basel). 2022-7-17

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