Canpolat Nur, Özdil Mine, Kuruğoğlu Sebuh, Çalışkan Salim, Sever Lale
Division of Pediatric Nephrology, İstanbul University Cerrahpaşa Faculty of Medicine, İstanbul, Turkey.
Turk J Pediatr. 2012 Nov-Dec;54(6):667-70.
Subcutaneous fat necrosis of the newborn is an uncommon disorder affecting the adipose tissue of term infants. It is usually known as a transient, benign and self-limited disease, characterized by painful skin lesions beginning within the first week of life. The prognosis of the disease is generally good, but it may be complicated by potentially life-threatening metabolic alterations, including hypercalcemia, thrombocytopenia, hypoglycemia, and hypertriglyceridemia. Hypercalcemia is the most serious complication of subcutaneous fat necrosis because of its effects on the renal and cardiovascular systems. We thereby present a case of subcutaneous fat necrosis with all these metabolic alterations, which was also complicated by nephrocalcinosis as a non-transient and serious complication.
新生儿皮下脂肪坏死是一种影响足月儿脂肪组织的罕见病症。它通常被认为是一种短暂、良性且自限性的疾病,其特征为出生后第一周内出现的疼痛性皮肤损害。该疾病的预后一般良好,但可能会并发潜在危及生命的代谢改变,包括高钙血症、血小板减少症、低血糖症和高甘油三酯血症。高钙血症是皮下脂肪坏死最严重的并发症,因为它会影响肾脏和心血管系统。我们在此呈现一例伴有所有这些代谢改变的皮下脂肪坏死病例,该病例还并发了肾钙质沉着症这一非短暂且严重的并发症。