Department of Neurology, SUNY-Downstate Medical Center, 450 Clarkson Avenue, Box 1213, Brooklyn, New York, 11203, USA.
Muscle Nerve. 2013 Jul;48(1):3-20. doi: 10.1002/mus.23771. Epub 2013 May 22.
In this review, we present an overview of the role of exercise in neuromuscular disease (NMD). We demonstrate that despite the different pathologies in NMDs, exercise is beneficial, whether aerobic/endurance or strength/resistive training, and we explore whether this benefit has a similar mechanism to that of healthy subjects. We discuss further areas for study, incorporating imaginative and novel approaches to training and its assessment in NMD. We conclude by suggesting ways to improve future trials by avoiding previous methodological flaws and drawbacks in this field.
在这篇综述中,我们介绍了运动在神经肌肉疾病(NMD)中的作用。我们证明,尽管 NMD 具有不同的病理学,但运动是有益的,无论是有氧/耐力训练还是力量/抗阻训练,我们还探讨了这种益处是否具有与健康受试者相似的机制。我们进一步讨论了研究领域,包括在 NMD 中训练及其评估的富有想象力和新颖的方法。最后,我们通过避免该领域以前的方法学缺陷和缺点,提出了改进未来试验的方法。