[Mechanism of the photodamage of eye structures. Changes in the lens crystalline charges after ultraviolet irradiation].

UV photodamaging action on individual soluble proteins of the cattle eye crystalline lens were studied by electrofocusing. The most quantitative and qualitative changes were found in gamma-crystallines: a decrease of original polypeptide stripes and appearance of additional components in pI 5.1-6.4 region. The illumination of alpha- and beta H-crystallines resulted in qualitative changes. The appearance of aggregates with the molecular mass above 10(6)D were noticed in all the protein fractions, except beta H-crystalline.