• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[褪黑素急性和慢性给药对大鼠在Y迷宫中重新学习及其对氟哌啶醇敏感性的影响]

[The effect of the acute and chronic administration of melatonin on the relearning of rats in a Y maze and their sensitivity to haloperidol].

作者信息

Ovanesov K B

出版信息

Farmakol Toksikol. 1990 Mar-Apr;53(2):15-7.

PMID:2369945
Abstract

After acute (10 mg/kg) and chronic (1 mg/kg, 10 days) administration melatonin facilitated parameters of rats relearning in the Y-maze. A simultaneous shortening of latency avoidance reaction was observed. Haloperidol (0.1 mg/kg) against the background of chronic melatonin administration more strongly optimized the animals' relearning. The hormonal action is supposed to depend on its sedative properties.

摘要

急性（10毫克/千克）和慢性（1毫克/千克，持续10天）给予褪黑素后，可促进大鼠在Y迷宫中重新学习的参数。同时观察到回避反应潜伏期缩短。在慢性给予褪黑素的背景下，氟哌啶醇（0.1毫克/千克）更有力地优化了动物的重新学习。推测这种激素作用取决于其镇静特性。

相似文献

1
[The effect of the acute and chronic administration of melatonin on the relearning of rats in a Y maze and their sensitivity to haloperidol].[褪黑素急性和慢性给药对大鼠在Y迷宫中重新学习及其对氟哌啶醇敏感性的影响]
Farmakol Toksikol. 1990 Mar-Apr;53(2):15-7.
2
[Effect of epiphysectomy on the relearning of rats in a U-shaped maze and their sensitivity to haloperidol].[骺切除术对大鼠在U型迷宫中再学习能力及其对氟哌啶醇敏感性的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Nov-Dec;39(6):1167-9.
3
[Dependence of the reversal training of rats in a Y-maze and their haloperidol sensitivity on the estrous cycle phase].[大鼠在Y迷宫中的反转训练及其对氟哌啶醇敏感性对发情周期阶段的依赖性]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1988 Nov-Dec;38(6):1093-7.
4
[Effect of neuroleptics on the retraining of rats to change the direction of the avoidance response in a Y-shaped maze].
Farmakol Toksikol. 1977 May-Jun;40(3):261-4.
5
[Removal of the optimizing action of neuroleptics on the avoidance behavior of rats after striatectomy].[纹状体切除术后抗精神病药物对大鼠回避行为优化作用的消除]
Farmakol Toksikol. 1979 May-Jun;42(3):230-4.
6
[The influence of melatonin, epiphysectomy and anaprilin on the cataleptogenic effect of haloperidol and its time dynamics].[褪黑素、松果体切除及心得安对氟哌啶醇致僵效应及其时间动态的影响]
Farmakol Toksikol. 1991 Jul-Aug;54(4):8-11.
7
[The role of microsomal oxidation processes in the development of haloperidol tolerance during melatonin administration and epiphysectomy in rats].[微粒体氧化过程在褪黑素给药及大鼠松果体切除术中氟哌啶醇耐受性发展中的作用]
Farmakol Toksikol. 1990 Sep-Oct;53(5):48-51.
8
Comparison of the impact of melatonin on chronic ethanol-induced learning and memory impairment between young and aged rats.褪黑素对年轻和老年大鼠慢性乙醇诱导的学习和记忆损伤影响的比较。
J Pineal Res. 2005 Nov;39(4):346-52. doi: 10.1111/j.1600-079X.2005.00257.x.
9
[Effect of constant darkness on relearning in a Y maze and on the temporal dynamics of forced swimming in rats of different ages].[持续黑暗对不同年龄大鼠在Y迷宫中重新学习及强迫游泳时间动态的影响]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1989 Mar-Apr;39(2):296-300.
10
Melatonin improves learning and memory performances impaired by hyperhomocysteinemia in rats.褪黑素可改善高同型半胱氨酸血症所致大鼠学习和记忆能力的损害。
Brain Res. 2005 Jun 7;1046(1-2):187-94. doi: 10.1016/j.brainres.2005.04.011.