Arushanian E B, Baturin V A
Farmakol Toksikol. 1979 May-Jun;42(3):230-4.
In an Y-maze rats easier reformed the trajectory of the behavioral response under the effect of haloperidol (0.05--0.1 mg/kg) and aminazin (0.5--1 mg/kg). A restricted (5--10 per cent of the volume) bilateral electrolytic distruction of the striatum fully suppressed the effect of lower doses of the above compounds both early (7--14th day) and late (28--35th day) after the operation. In large doses the neuroleptics continued to facilitate relearning of the rats in the first 1--2 weeks following striatectomy, but later on this effect also disappeared.
在Y型迷宫中，大鼠在氟哌啶醇（0.05 - 0.1毫克/千克）和氯丙嗪（0.5 - 1毫克/千克）作用下更容易改变行为反应轨迹。纹状体双侧局限性（体积的5 - 10%）电解损毁在手术后早期（第7 - 14天）和晚期（第28 - 35天）完全抑制了上述化合物低剂量的作用。大剂量时，在纹状体切除后的前1 - 2周内，这些抗精神病药物仍能促进大鼠的重新学习，但之后这种作用也消失了。
