Kresiun V I, Kravchenko L S, Kadyrova L L
Farmakol Toksikol. 1990 Mar-Apr;53(2):29-31.
The effect of piracetam on the dynamics of the infarction development, free radical lipid peroxidation in the myocardium and the immunological reactivity was studied on dogs with experimental myocardial infarction during the course and prophylactic treatment. The antiarrhythmic, antihypoxic, antioxidant effects of the drug, its positive influence on the parameters of humoral and cellular immunity were revealed. The comparative assessment of piracetam action during cardiogenic stress caused by myocardial infarction showed a higher pharmacological effect in therapeutic use.
在实验性心肌梗死犬的病程和预防性治疗过程中,研究了吡拉西坦对梗死发展动态、心肌自由基脂质过氧化及免疫反应性的影响。揭示了该药物的抗心律失常、抗缺氧、抗氧化作用,及其对体液和细胞免疫参数的积极影响。对心肌梗死所致心源性应激期间吡拉西坦作用的比较评估表明,其在治疗应用中具有更高的药理效应。