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[吡拉西坦在心肌梗死患者中的治疗应用]

[Therapeutic use of piracetam in myocardial infarct patients].

作者信息

Leshchinskiĭ L A, Pimenov L T, Fedorov V S

出版信息

Kardiologiia. 1987 Feb;27(2):46-50.

PMID:3573522
Abstract

Fifty-four patients with acute myocardial infarction were evaluated repeatedly, with 28 of those treated with piracetam, and 26 used as controls. Piracetam produced a considerable favorable effect on the clinical course of myocardial infarction, as reflected in a more rapid clinical improvement of acute circulatory insufficiency and an analgetic effect. The drug reduced heart rate and moderately elevated systolic arterial blood pressure. Positive changes in total CPK, LDH, AST and ALT activities, and in ECG from 12 and 35 leads were quicker to come.

摘要

对54例急性心肌梗死患者进行了反复评估,其中28例接受了吡拉西坦治疗,26例作为对照。吡拉西坦对心肌梗死的临床病程产生了相当显著的有利影响,表现为急性循环功能不全的临床改善更快以及具有镇痛作用。该药降低了心率,并适度升高了收缩期动脉血压。总肌酸磷酸激酶(CPK)、乳酸脱氢酶(LDH)、天门冬氨酸氨基转移酶(AST)和丙氨酸氨基转移酶(ALT)活性以及12导联和35导联心电图的阳性变化出现得更快。

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