Seo Seok In, Yu Chang Sik, Kim Gwon Sik, Lee Jong Lyul, Yoon Yong Sik, Kim Chan Wook, Lim Seok-Byung, Kim Jin Cheon
Department of Colon & Rectal Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Ann Coloproctol. 2013 Apr;29(2):66-71. doi: 10.3393/ac.2013.29.2.66. Epub 2013 Apr 30.
A diverting stoma is known to reduce the consequences of distal anastomotic failure following colorectal surgery. The aim of this study was to evaluate the efficacy of a diverting stoma after an ultra-low anterior resection (uLAR) for rectal cancer.
Between 2000 and 2007, 836 patients who underwent an uLAR were divided into two groups, depending on the fecal diversion: 246 received fecal diversion, and 590 had no diversion. Patient- and disease-related variables were compared between the two groups.
Thirty-two of the 836 patients (3.8%) had immediate anastomosis-related complications and required reoperation. Anastomosis leakage comprised 72% of the complications (23/32). The overall immediate complication rate was significantly lower in patients with a diverting stoma (0.8%, 2/246) compared to those without a diverting stoma (5.1%, 30/590; P = 0.005). The fecal diversion group had lower tumor location, lower anastomosis level, and more preoperative chemo-radiation therapy (P < 0.001). In total, 12% of patients in the diverting stoma group had complications either in making or reversing the stoma (30/246).
The diverting stoma decreased the rate of immediate anastomosis-related complications. However, the rate of complications associated with the diverting stoma was non-negligible, so strict criteria should be applied when deciding whether to use a diverting stoma.
已知转流造口可减轻结直肠手术后远端吻合口失败的后果。本研究的目的是评估直肠癌超低位前切除术(uLAR)后转流造口的疗效。
2000年至2007年间,836例行uLAR的患者根据粪便转流情况分为两组:246例接受粪便转流,590例未行转流。比较两组患者和疾病相关变量。
836例患者中有32例(3.8%)发生了与吻合口直接相关的并发症并需要再次手术。吻合口漏占并发症的72%(23/32)。与未行转流造口的患者相比,行转流造口的患者总体直接并发症发生率显著更低(0.8%,2/246 vs. 5.1%,30/590;P = 0.005)。粪便转流组肿瘤位置更低、吻合口水平更低且术前接受放化疗更多(P < 0.001)。总的来说,转流造口组12%的患者在造口形成或回纳时出现并发症(30/246)。
转流造口降低了与吻合口直接相关的并发症发生率。然而,与转流造口相关的并发症发生率不可忽视,因此在决定是否使用转流造口时应应用严格的标准。