Critoph Christopher H, Patel Vimal, Mist Bryan, Thomas Martin D, Elliott Perry M
The Heart Hospital, Institute for Cardiovascular Science, University College London, London, UK.
Clin Physiol Funct Imaging. 2013 Sep;33(5):338-43. doi: 10.1111/cpf.12032. Epub 2013 Apr 3.
We sought to determine the accuracy of finger plethysmography using pulse waveform analysis with brachial calibration for measurement of cardiac output during submaximal exercise by comparing it against an acetylene (C2H2) uptake technique.
The study included 24 healthy volunteers (12 males, age 35 ± 8 years). Testing was performed on an upright cycle ergometer using an incremental protocol. Cardiac output measurements were performed at rest and during sub-maximal exercise using a single breath C2H2 uptake technique and continuously using finger plethysmography with brachial calibration.
Valid results at rest and during sub-maximal exercise were achieved in 20 of 24 participants. Cardiac output at rest was 5.3 ± 1.1 and 5.2 ± 1.2 l min(-1) for finger plethysmography and C2H2, respectively, P = 0.712. Mean difference between techniques was -0.1 ± 0.5 l min(-1). Cardiac output during submaximal exercise was 10.2 ± 2.3 and 10.3 ± 2.1 l min(-1) for finger plethysmography and C2H2, respectively, P = 0.898. Mean difference between techniques was 0.1 ± 1.5 l min(-1). The overall correlation between finger plethysmography and C2H2 data obtained during rest and exercise was r(2) = 0.872, P<0.0001. Mean rise in cardiac output during exercise was 4.9 ± 1.5 (finger plethysmography) and 5.1 ± 1.5 l min(-1) (C2H2), P = 0.64.
Finger plethysmography determined cardiac output values both at rest and during sub-maximal exercise are comparable with those obtained using a single breath C2H2 uptake technique.
我们试图通过将其与乙炔（C2H2）摄取技术进行比较，来确定使用带有肱动脉校准的脉搏波形分析的手指体积描记法在次最大运动期间测量心输出量的准确性。
该研究纳入了24名健康志愿者（12名男性，年龄35±8岁）。使用递增方案在直立式自行车测力计上进行测试。使用单次呼吸C2H2摄取技术在静息和次最大运动期间进行心输出量测量，并使用带有肱动脉校准的手指体积描记法持续进行测量。
24名参与者中有20名获得了静息和次最大运动期间的有效结果。手指体积描记法和C2H2在静息时的心输出量分别为5.3±1.1和5.2±1.2升/分钟，P = 0.712。两种技术之间的平均差异为-0.1±0.5升/分钟。手指体积描记法和C2H2在次最大运动期间的心输出量分别为10.2±2.3和10.3±2.1升/分钟，P = 0.898。两种技术之间的平均差异为0.1±1.5升/分钟。静息和运动期间获得的手指体积描记法与C2H2数据之间的总体相关性为r(2)=0.872，P<0.0001。运动期间心输出量的平均增加量为4.9±1.5（手指体积描记法）和5.1±1.5升/分钟（C2H2），P = 0.64。
手指体积描记法测定的静息和次最大运动期间的心输出量值与使用单次呼吸C2H2摄取技术获得的值相当。
